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Published on: May 26, 2023
Association between mechanical power during one-lung ventilation and pulmonary complications after thoracoscopic lung
Hong-Mei Liu1,2, Gong-Wei Zhang3, Hong Yu1
1Department of Anesthesiology, West China Hospital, Sichuan University, Chengdu, 610041, China.
Background:
The role of mechanical power on pulmonary outcomes after thoracic surgery with one-lung ventilation was unclear. We investigated the association between mechanical power and postoperative pulmonary complications in patients undergoing thoracoscopic lung resection surgery.
Methods:
In this single-center, prospective observational study, 622 patients scheduled for thoracoscopic lung resection surgery were included. Volume control mode with lung protective ventilation strategies were implemented in all participants. The primary endpoint was a composite of postoperative pulmonary complications during hospital stay. Multivariable logistic regression models were used to evaluate the association between mechanical power and outcomes.
Results:
The incidence of pulmonary complications after surgery during hospital stay was 24.6% (150 of 609 patients). The multivariable analysis showed that there was no link between mechanical power and postoperative pulmonary complications.
Conclusions:
In patients undergoing thoracoscopic lung resection with standardized lung-protective ventilation, no association was found between mechanical power and postoperative pulmonary complications.
Trial Registration:
Trial registration number: ChiCTR2200058528, date of registration: April 10, 2022.
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