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Taurine Alleviates Experimental Colitis by Enhancing Intestinal Barrier Function and Inhibiting Inflammatory Response

Jiaming Zheng1,2, Jinglin Zhang1,2, Yewen Zhou1,2

  • 1College of Veterinary Medicine, Yangzhou University, Yangzhou 225009, People's Republic of China.

Journal of Agricultural and Food Chemistry
|May 18, 2024
PubMed
Summary

Taurine deficiency worsens ulcerative colitis (UC) in mice. Supplementing with taurine protects the gut barrier and reduces inflammation by inhibiting the TLR4/NF-κB pathway, suggesting taurine is a promising treatment for colitis.

Keywords:
TLR4/NF-κB pathwayinflammationintestinal barrier functiontaurineulcerative colitis

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