Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

  1. Home
  3. Preoperative Factors Associated With Lateral Lymph Node Metastasis In Lower Rectal Cancer And The Evaluation Of The Middle Rectal Artery.
  1. Home
  3. Preoperative Factors Associated With Lateral Lymph Node Metastasis In Lower Rectal Cancer And The Evaluation Of The Middle Rectal Artery.

Related Experiment Video

Robot-assisted Total Mesorectal Excision and Lateral Pelvic Lymph Node Dissection for Locally Advanced Middle-low Rectal Cancer
12:45

Robot-assisted Total Mesorectal Excision and Lateral Pelvic Lymph Node Dissection for Locally Advanced Middle-low Rectal Cancer

Published on: February 12, 2022

5.6K

Preoperative factors associated with lateral lymph node metastasis in lower rectal cancer and the evaluation of the

Takuya Shiraishi1, Hiroomi Ogawa1, Arisa Yamaguchi1

  • 1Department of General Surgical Science, Gunma University Graduate School of Medicine, 3-39-22 Showa-Machi, Maebashi, Gunma, 371-8511, Japan.

Surgery Today
|May 19, 2024

View abstract on PubMed

Summary
This summary is machine-generated.

Preoperative evaluation using imaging and clinical factors can help exclude lateral lymph node dissection (LLND) in rectal cancer patients. Combining PET/CT and clinical lateral lymph node assessment improves accuracy in identifying cases where LLND is not necessary.

Keywords:
Computed tomographyLateral lymph nodeMiddle rectal arteryNegative predictive valuePositron emission tomographyPreoperative diagnosis

More Related Videos

Clinical Application of Single-Surgeon, Three-Port, Laparoscopic Resection for Colorectal Cancer with Natural Orifice Specimen Extraction
08:26

Clinical Application of Single-Surgeon, Three-Port, Laparoscopic Resection for Colorectal Cancer with Natural Orifice Specimen Extraction

Published on: March 24, 2023

457
Sentinel Lymph Node Mapping and Biopsy for Endometrial Cancer at Early Stage with Laparoscopy
05:52

Sentinel Lymph Node Mapping and Biopsy for Endometrial Cancer at Early Stage with Laparoscopy

Published on: August 19, 2021

11.4K

Related Experiment Videos

Robot-assisted Total Mesorectal Excision and Lateral Pelvic Lymph Node Dissection for Locally Advanced Middle-low Rectal Cancer
12:45

Robot-assisted Total Mesorectal Excision and Lateral Pelvic Lymph Node Dissection for Locally Advanced Middle-low Rectal Cancer

Published on: February 12, 2022

5.6K
Clinical Application of Single-Surgeon, Three-Port, Laparoscopic Resection for Colorectal Cancer with Natural Orifice Specimen Extraction
08:26

Clinical Application of Single-Surgeon, Three-Port, Laparoscopic Resection for Colorectal Cancer with Natural Orifice Specimen Extraction

Published on: March 24, 2023

457
Sentinel Lymph Node Mapping and Biopsy for Endometrial Cancer at Early Stage with Laparoscopy
05:52

Sentinel Lymph Node Mapping and Biopsy for Endometrial Cancer at Early Stage with Laparoscopy

Published on: August 19, 2021

11.4K

Area of Science:

  • Oncology
  • Surgical Oncology
  • Radiology

Background:

  • Lateral lymph node metastasis is a critical factor in rectal cancer staging and treatment.
  • Determining the necessity of lateral lymph node dissection (LLND) preoperatively can optimize surgical planning and patient outcomes.

Purpose of the Study:

  • To identify preoperative factors, including middle rectal artery (MRA) evaluation, that predict lateral lymph node (LLN) metastasis in rectal cancer.
  • To establish criteria for excluding LLND in select rectal cancer patients.

Main Methods:

  • Retrospective analysis of 55 rectal cancer patients who underwent total mesorectal excision with LLND.
  • Preoperative evaluation included positron emission tomography-computed tomography (PET/CT) and assessment of clinical LLN (cLLN) metastasis.
  • Analysis of middle rectal artery (MRA) presence and location relative to LLN metastasis.

    • Main Results:

    • Pathological LLN metastasis (pLLN) was observed in 23.6% of patients.
    • Clinical LLN metastasis (short-axis size) and PET/CT findings were independent predictors of pLLN metastasis.
    • A high negative predictive value (97.1%) was achieved when combining PET/CT and cLLN short-axis size.
    • The presence of MRA was significantly associated with pLLN metastasis, particularly in the internal iliac region.

    Conclusions:

    • Combined assessment of cLLN metastasis (short-axis size) and PET/CT status offers a high negative predictive value for pLLN metastasis.
    • This combined approach can help identify rectal cancer patients for whom LLND can be safely excluded.
    • MRA presence is a significant predictor of LLN metastasis, aiding in risk stratification.