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Published on: November 30, 2022
A Comprehensive Review on Benzofuran Synthesis Featuring Innovative and Catalytic Strategies
Aqsa Mushtaq1, Ameer Fawad Zahoor1, Sajjad Ahmad2
1Department of Chemistry, Government College University Faisalabad, 38000 Faisalabad, Pakistan.
Abstract:
Benzofurans have intrigued both pharmaceutical researchers and chemists owing to the medicinal usage of their derivatives against copious disease-causing agents (i.e., bacteria, viruses, and tumors). These heterocyclic scaffolds are pervasively encountered in a number of natural products and drugs. The ever-increasing utilization of benzofuran derivatives as pharmaceutical agents persuaded the chemists to devise novel and facile methodological approaches to assemble the biologically potent benzofuran nucleus. This review summarizes the current developments regarding the innovative synthetic routes and catalytic strategies to procure the synthesis of benzofuran heterocycles with their corresponding mechanistic details, reported by several research groups during 2021-2023.
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