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Diffuse Unilateral Subacute Neuroretinitis: Challenges in Diagnosis and Management
Mustafa Nurul-Farhana1,2, Abdul Aziz Roslin-Azni2, Tan Sor-Earn3
1Department of Ophthalmology and Visual Sciences, School of Medical Sciences, Universiti Sains Malaysia, Kubang Kerian, MYS.
Cureus
|May 20, 2024
Summary
Diffuse unilateral subacute neuroretinitis (DUSN) can be challenging to diagnose. Multimodal imaging aids in identifying the nematode, leading to successful treatment with albendazole.
Area of Science:
- Ophthalmology
- Infectious Diseases
- Parasitology
Background:
- Diffuse unilateral subacute neuroretinitis (DUSN) is an inflammatory eye condition often caused by nematode parasites.
- Early diagnosis and treatment are crucial for preserving vision.
Observation:
- Two cases of DUSN are presented, showcasing varied clinical presentations.
- Multimodal imaging, including fundus photography and optical coherence tomography (OCT), was instrumental in visualizing the nematode in both patients.
- One case exhibited migrating choroiditis, while the other presented with extensive exudative retinal detachment.
Findings:
- Both patients received a six-week course of oral albendazole.
- The first patient also underwent argon laser photocoagulation targeting the suspected nematode.
- Successful resolution of ocular inflammation and no recurrence were observed in both cases post-treatment.
Implications:
- DUSN should be considered in young, healthy individuals presenting with unexplained unilateral visual loss and ocular inflammation.
- This case series underscores the diagnostic challenges in identifying the causative nematode in DUSN.
- Multimodal imaging plays a vital role in the diagnosis and management of DUSN.
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