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Updated: Jun 26, 2025

Size Matters: Measurement of Capsule Diameter in Cryptococcus neoformans
Published on: February 27, 2018
Haematologic and Urologic Manifestations of Cryptococcus neoformans
Jessica Morgan1, John Vardanega1, Mimi Yue2,3
1Infectious Diseases, Department of Medicine, Mater Public Hospital, South Brisbane, Queensland, Australia.
Abstract:
Cryptococcus neoformans classically causes pulmonary and central nervous system (CNS) infection in immunocompromised hosts and can lead to disseminated disease. Two cases of atypical cryptococcal infection are presented-an elderly Human Immunodeficiency Virus- (HIV-) negative male with a urinary source of infection and a young HIV-positive male with bone marrow infiltration complicated by haemophagocytic lymphohistiocytosis (HLH). A literature review of systemic cryptococcal infections involving the genitourinary tract and bone marrow was performed. These cases highlight the importance of clinicians considering uncommon manifestations of cryptococcal disease.
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