Related Experiment Video
Updated: Jun 26, 2025

Adjunctive Diode Laser Therapy and Probiotic Lactobacillus Therapy in the Treatment of Periodontitis and Peri-Implant Disease
Published on: May 9, 2022
Close follow-up instead of antibiotic therapy after mandibular third molar surgery: A clinical trial
Mohammad Mehdizadeh1, Alireza Sharifinejad2, Shokoufeh Aghayari1
1Department of Oral and Maxillofacial Surgery, School of Dentistry, Qom University of Medical Sciences, Qom, Iran.
Background:
Prescribing antibiotics (AB) before or after third molar surgery is common among dentists and oral surgeons; however the effectiveness of AB therapy in reducing surgery complications is still contradictory.
Aim:
The aim of this study is to evaluate the healing process after mandibular third molar surgery without AB therapy and to assess the role of close follow-ups on patient's perspective.
Methods:
This study is a semi-empirical, prospective study conducted on 79 healthy patients. After surgical extraction of the impacted or semi-erupted mandibular third molar, assessment of pain, swelling (intergonial width), infection, and sub-periosteal abscess was done during the 1-month follow-ups of patients.
Results:
The mean difficulty level of surgeries performed in this study was moderate. A significant relationship was found between the pain intensity and the psychological impact of follow-ups (p < 0.05). No fever or sign of infection were seen in any patient. The amount of swelling was significantly related to the difficulty level of surgery (p = 0.001); however, no significant correlation was found between the amount of pain and the level of difficulty.
Conclusion:
Within the limitations of this study, it can be concluded that in order to reduce the hazards of AB therapy, close follow-up of patients after surgery can be advised.

