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Published on: July 5, 2022
Rising tide: The global surge of type 2 diabetes in children and adolescents demands action now
Joseph M Pappachan1,2,3, Cornelius James Fernandez4, Ambika P Ashraf5
1Department of Endocrinology and Metabolism, Lancashire Teaching Hospitals NHS Trust, Preston PR2 9HT, United Kingdom.
Insights
Childhood obesity and type 2 diabetes (T2DM) are rising globally due to environmental and genetic factors. Urgent action is needed to manage this growing public health crisis and prevent future complications.
Area of Science:
- Pediatrics
- Endocrinology
- Public Health
Background:
- Childhood-onset obesity is a significant global public health issue.
- It is driven by obesogenic environments and genetic/epigenetic factors.
- This has led to a sharp increase in type 2 diabetes mellitus (T2DM) among children and adolescents.
Discussion:
- The rising incidence of T2DM in youth poses a substantial threat of early-onset complications.
- This trend is expected to place immense strain on global healthcare systems.
- Addressing this requires a coordinated global response involving research, policy, and social initiatives.
Key Insights:
- Understanding the epidemiological trends of childhood obesity and T2DM is critical.
- Exploring the risks, consequences, and pathobiology of pediatric obesity is essential for effective management.
- Evidence-based strategies are needed to combat the growing problem of diabesity.
Outlook:
- Multifaceted research efforts are crucial to understand and combat childhood obesity and T2DM.
- Governmental legislation and policy changes are vital for creating healthier environments.
- Effective social action and public health campaigns are necessary to curb the epidemic and its long-term impact.
Abstract:
Childhood-onset obesity has emerged as a major public healthcare challenge across the globe, fueled by an obesogenic environment and influenced by both genetic and epigenetic predispositions. This has led to an exponential rise in the incidence of type 2 diabetes mellitus in children and adolescents. The looming wave of diabetes-related complications in early adulthood is anticipated to strain the healthcare budgets in most countries. Unless there is a collective global effort to curb the devastation caused by the situation, the impact is poised to be pro-found. A multifaceted research effort, governmental legislation, and effective social action are crucial in attaining this goal. This article delves into the current epidemiological landscape, explores evidence concerning potential risks and consequences, delves into the pathobiology of childhood obesity, and discusses the latest evidence-based management strategies for diabesity.
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