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Recurrent Spinal Arteriovenous Malformations in a Patient with Cobb Syndrome
Nicholas Mulchan1, Mekka R Garcia1, John T Wells1
1Department of Neurology, NYU Langone Health, New York, NY, USA.
Cobb syndrome, a rare neurocutaneous disease, involves spinal vascular anomalies and skin lesions. Early diagnosis and treatment of spinal arteriovenous malformations (AVMs) are crucial for managing symptoms like pain and weakness.
Area of Science:
- Neurology
- Vascular Surgery
- Dermatology
Background:
- Cobb syndrome is a rare neurocutaneous disorder.
- It presents with spinal vascular anomalies and corresponding dermatomal skin lesions.
Observation:
- A 12-year-old boy with a history of spinal arteriovenous malformation (AVM) and a thoracic hyperpigmented patch presented with back pain and lower extremity weakness.
- Imaging revealed extensive Type III AVMs in spinal and paraspinal tissues (T4-T7), with a 4mm anterior spinal artery aneurysm.
Findings:
- The patient underwent embolization of the spinal AVM and the anterior spinal artery aneurysm.
- Complete occlusion of the aneurysm was achieved with partial embolization of the main AVM nidus.
Implications:
- This case highlights the importance of early diagnosis and comprehensive management of Cobb syndrome.
- Understanding the natural history and recurrence risk aids in improving patient outcomes.
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