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Published on: January 17, 2018
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Retraction Note: Autoantibodies detection in patients affected by autoimmune retinopathies
M R Ceccarini1, M C Medori, K Dhuli
1Department of Pharmaceutical Sciences, University of Perugia, Perugia, Italy.
Summary
This study on autoantibodies in autoimmune retinopathies was retracted due to ethical approval issues and undeclared conflicts of interest. Concerns about potential figure manipulation led to doubts about the integrity of the findings.
Area of Science:
- Ophthalmology
- Immunology
- Medical Ethics
Background:
- Autoimmune retinopathies are a group of rare, debilitating eye diseases.
- Autoantibodies play a crucial role in the pathogenesis of autoimmune conditions.
- Accurate detection of autoantibodies is vital for diagnosing and managing autoimmune retinopathies.
Purpose of the Study:
- To investigate the presence and significance of autoantibodies in patients with autoimmune retinopathies.
- To evaluate the diagnostic utility of specific autoantibodies in this patient population.
Main Methods:
- The study involved the analysis of autoantibody profiles in a cohort of patients diagnosed with autoimmune retinopathies.
- Various immunological assays were employed for autoantibody detection.
- Ethical considerations and conflict of interest disclosures were part of the study's protocol.
Main Results:
- The investigation into the manuscript revealed major flaws, including issues with ethical approval and an undeclared conflict of interest.
- Concerns were raised regarding potential manipulation of Supplementary Figure 2, leading to divergent evaluations.
- The Editor in Chief expressed doubts about the integrity of the presented findings.
Conclusions:
- The article "Autoantibodies detection in patients affected by autoimmune retinopathies" has been retracted by the journal.
- The retraction was based on significant concerns regarding ethical approval, conflict of interest, and potential data manipulation.
- The publisher apologizes for any inconvenience caused by the retraction.

