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Updated: Jun 26, 2025

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A Comprehensive Review on the Significance of Cysteine in Various Metabolic Disorders; Particularly CVD, Diabetes,

Namra Aziz1, Pranay Wal1, Rishika Sinha1

  • 1PSIT-Pranveer Singh Institute of Technology (Pharmacy), NH-19, Kanpur-209305, UP, India.

Current Protein & Peptide Science
|May 20, 2024
PubMed

Insights

Cysteine shows promise in preventing and treating metabolic disorders by targeting reactive oxygen species. This review explores its potential to combat conditions like diabetes, cardiovascular disease, and stroke.

Area of Science:

  • Biochemistry
  • Pathology
  • Nutritional Science

Background:

  • Metabolic disorders, including diabetes, cardiovascular disorders (CVD), renal dysfunction, and ischemic stroke, are leading causes of adult mortality.
  • Reactive oxygen species (ROS) are a primary etiological factor in metabolic syndrome and associated diseases.
  • Current treatments for metabolic disorders offer limited efficacy and pose significant health risks.

Purpose of the Study:

  • To review the potential of cysteine as a therapeutic agent for metabolic disorders.
  • To investigate cysteine's role in eradicating reactive oxygen species.
  • To assess cysteine's efficacy in preventing and treating prevalent metabolic diseases.

Main Methods:

  • Literature review of studies on cysteine and metabolic disorders.
  • Analysis of research on the antioxidant properties of cysteine.
  • Exploration of cysteine's impact on disease pathways related to ROS.

Main Results:

  • Cysteine, an amino acid, demonstrates potential in addressing metabolic disorders.
  • Evidence suggests cysteine can neutralize reactive oxygen species.
  • Cysteine may offer a novel therapeutic strategy for conditions like CVD and diabetes.

Conclusions:

  • Cysteine holds promise for the prevention and treatment of major metabolic disorders.
  • Targeting reactive oxygen species with cysteine could mitigate disease progression.
  • Further research into cysteine's therapeutic applications is warranted.

Keywords:
Cysteinecardiovascular disorders.diabetes mellitusischemic strokemetabolic disordersreactive oxygen speciesrenal dysfunction

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