Related Experiment Video
Updated: Jun 26, 2025

Post-Myocardial Infarction Heart Failure in Closed-chest Coronary Occlusion/Reperfusion Model in Göttingen Minipigs and Landrace Pigs
Published on: April 17, 2021
Post-Covid Conditions and their Effects on the Cardiovascular System
M Osadchuk1, I Kolesnikova2, L Zakharova2
1Department of Polyclinic Therapy, I.M. Sechenov First Moscow State Medical University (Sechenov University), Moscow, Russian Federation.
Insights
Post-COVID conditions include persistent symptoms like anosmia and dyspnea, with cardiovascular issues affecting 15.8% of patients. Middle-aged individuals show the highest cardiovascular disease rates after COVID-19 recovery.
Area of Science:
- Cardiology
- Infectious Diseases
- Public Health
Background:
- COVID-19's global impact necessitates research into its long-term effects.
- Understanding post-COVID conditions and cardiovascular complications is crucial due to varied symptoms and limited antiviral treatments.
Purpose of the Study:
- To analyze post-COVID conditions and clinical manifestations of cardiovascular lesions in recovering patients.
- To investigate the prevalence and types of cardiovascular issues following COVID-19 infection.
Main Methods:
- Prospective cohort study of 250 COVID-19 patients (June-August 2021).
- Focused analysis on 200 patients with elevated troponin levels post-hospitalization.
- Assessed cardiovascular variables: tachycardia, ischemia, heart attack, myocarditis, hypertension, blood clots, heart failure.
Main Results:
- Persistent symptoms include anosmia/ageusia (59%), dyspnea (36.7%), and cardiovascular complaints (15.8%).
- Symptom reduction observed by day 60 (5-10%) and activity decrease by day 90 (25-35%).
- Patients aged 40-60 years had the highest incidence of cardiovascular diseases (75%).
Conclusions:
- SARS-CoV-2 infection highlights the critical need for cardiological attention.
- Cardiac screening reveals a high prevalence of serious heart problems in COVID-19 patients.
- Specialized cardiac care and vigilance are essential for managing COVID-19 patients.
Background:
Rising global concerns about COVID-19 recently gained more research attention due to the ease of person-to-person transmission, various symptoms after healing, and the shortage of effective antiviral therapy. The study aims to analyze post-COVID conditions and clinical manifestations of cardiovascular lesions in patients recovering from COVID-19 infection.
Methods:
A practical examination of post-COVID conditions manifestation was conducted in a prospective cohort study, involving 250 patients diagnosed with COVID-19 between June 1, 2021, and August 31, 2021. The study specifically focused on analyzing the cardiovascular effects of COVID-19, utilizing data from a subgroup of 200 patients previously discharged from the hospital with elevated troponin levels. The cardiovascular variables assessed included tachycardia, ischemia, heart attack, myocarditis, hypertension, blood clots, and heart failure.
Results:
It has been observed that among surviving patients, the following symptoms persisted: anosmia/ageusia (59%), severe dyspnea (36.7%), palpitations and complaints related to the cardiovascular sys-tem (15.8%), headaches (13.2%), arthralgia (11.7%), myalgia (9.8%), and hair problems (≥5%). By the 60th day, a reduction in symptoms by 5-10% was noted, and by the 90th day, a decrease in activity by 25-35% was observed. Patients aged 40-60 years exhibited the highest percentage of cardiovascular diseases (75%).
Conclusions:
Consequently, the SARS-CoV-2 virus underscores the critical importance of cardiological attention in patient care. Cardiac screening results in individuals with COVID-19 reveal a significant prevalence of serious heart problems, affecting over half of the patients. This emphasizes the necessity for heightened vigilance and specialized cardiac care when managing patients with COVID-19.
Related Concept Videos
Exercise and Cardiovascular Response
Light to moderate physical activity initiates a series of interconnected responses in the body. The heart rate modestly increases in anticipation of the workout, followed by widespread vasodilation as oxygen consumption by skeletal muscles increases. This results in decreased peripheral resistance, increased capillary blood flow, and accelerated...
Psychoneuroimmunology: Cardiovascular Disease
A key area of focus in PNI is the relationship between stress and coronary...
Assessment of the Cardiovascular System I: Subjective Data
Initial Enquiry
Ask the patient about their primary concern and thoroughly explore all reported symptoms.
Medical History
Investigate past illnesses affecting the cardiovascular system, such as angina, anemia, rheumatic fever, congenital heart disease, stroke, thrombophlebitis, dysrhythmias, varicosities
Inquire about symptoms...
Imbalances in Cardiac Output
CHF can occur due to the failure of either side of the heart. Left-side failure leads to pulmonary congestion—the right side continues to send...
Cardiovascular Drugs: Classification based on Therapeutic Indications
Pathophysiology of Cardiac Performance

