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Induction and Assessment of Exertional Skeletal Muscle Damage in Humans
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Eccentric Exercise-Induced Muscle Damage Reduces Gross Efficiency.

Daniel Horner1, Owen Jeffries, Callum G Brownstein

  • 1School of Biomedical, Nutritional, and Sport Sciences, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne, UNITED KINGDOM.

Medicine and Science in Sports and Exercise
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Summary
This summary is machine-generated.

Eccentric exercise-induced muscle damage (EIMD) reduces gross cycling efficiency, likely due to increased muscle activation. Delta efficiency remained unchanged, possibly due to measurement limitations.

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Area of Science:

  • Exercise Physiology
  • Sports Science
  • Muscle Physiology

Background:

  • Eccentric exercise-induced muscle damage (EIMD) is common after strenuous physical activity.
  • The impact of EIMD on cycling efficiency and cardiopulmonary responses remains largely uninvestigated.

Purpose of the Study:

  • To investigate the effects of EIMD on gross and delta cycling efficiency.
  • To assess the influence of EIMD on cardiopulmonary responses during cycle ergometry.

Main Methods:

  • Recreational athletes underwent cycling tests at varying intensities (70%, 90%, 110% GET) under control and EIMD conditions.
  • Maximal voluntary contraction, potentiated twitch, and voluntary activation were measured.
  • Gross and delta efficiency were determined via indirect calorimetry; cardiopulmonary responses and EMG RMS were recorded.

Main Results:

  • EIMD significantly reduced maximal voluntary contraction and gross cycling efficiency across all tested intensities.
  • Cycling EMG RMS was higher in the EIMD condition, suggesting increased muscle activation.
  • Cardiopulmonary responses like breath frequency and V̇E/V̇CO2 increased with intensity, notably higher in the EIMD group at 110% GET.

Conclusions:

  • EIMD impairs gross cycling efficiency, potentially mediated by heightened muscle activation.
  • Delta efficiency showed no significant change, possibly due to its inherent measurement variability.
  • EIMD-related hyperventilation is intensity-dependent and may involve central command alterations.