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Roux-en-Y Gastric Bypass Operation in Rats
Published on: June 11, 2012
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Comprehensive outcomes after Roux-en-Y gastric bypass with a near-complete 15-year follow-up
Noura Jawhar1, Kamal Abi Mosleh1, Katarzyna Z Bartosiak1
1Department of Surgery, Mayo Clinic, Rochester, MN.
Surgery
|May 20, 2024
Summary
Laparoscopic Roux-en-Y gastric bypass offers sustained weight loss and resolves obesity-related conditions for up to 15 years. This bariatric surgery demonstrates long-term durability and safety, crucial for managing obesity and its comorbidities.
Area of Science:
- Bariatric Surgery
- Metabolic Surgery
- Obesity Medicine
Background:
- Laparoscopic Roux-en-Y gastric bypass (LRYGB) is established for short-term outcomes.
- Limited data exists on LRYGB outcomes beyond 10 years.
- Long-term durability and safety require further investigation.
Purpose of the Study:
- To evaluate the long-term (15-year) durability and safety of LRYGB.
- To assess sustained weight loss and resolution of obesity-related conditions.
- To identify factors influencing long-term outcomes.
Main Methods:
- Single-center retrospective cohort study.
- Included patients who underwent primary LRYGB between 2008-2009.
- Follow-up of at least 14 years, analyzing weight loss, comorbidity resolution/recurrence, and mortality.
Main Results:
- Mean weight loss remained >20% throughout follow-up.
- Remission rates: 60.8% for type 2 diabetes, 46.7% for dyslipidemia, 40% for hypertension.
- Weight recurrence rate was 51.1% at 15 years, predicted by higher BMI and preoperative diabetes.
Conclusions:
- LRYGB provides sustainable weight loss over 15 years.
- Obesity-related medical conditions show sustained resolution for ≥10 years.
- LRYGB demonstrates long-term efficacy and safety for obesity management.
