Analysis of MRI features and associated factors of the pituitary neuroendocrine tumor streaky sign

  • 0Department of Neurosurgery, Fuzhou 900th Hospital, Fuzong Clinical Medical College of Fujian Medical University, Fuzhou, China.

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Summary

This summary is machine-generated.

The streaky sign on MRI for pituitary neuroendocrine tumors may indicate a dilated sinus or blood vessel. Its direction aligns with tumor expansion, potentially supporting long-distance growth.

Area Of Science

  • Radiology
  • Neuro-oncology
  • Endocrinology

Background

  • Pituitary neuroendocrine tumors (PitNETs) are common intracranial neoplasms.
  • The
  • streaky sign
  • on MRI is a newly observed imaging feature in some PitNETs.

Purpose Of The Study

  • To analyze the imaging features of PitNETs with the streaky sign.
  • To investigate the relationship between the streaky sign's direction and the tumor's optimal expansion direction.

Main Methods

  • Retrospective analysis of 237 PitNET patient MR images.
  • Definition of the streaky sign: >10 mm high signal on T1WI with enhancement.
  • Comparison of 33 patients with streaky signs versus 33 without.

Main Results

  • 85 streaky signs were identified.
  • Average deviation between streaky sign direction and optimal tumor extension was ~11°.
  • Strong positive correlation (r=0.967) between longest streaky sign angle and optimal tumor extension angle.

Conclusions

  • The streaky sign may represent a dilated sinus or small blood vessel.
  • The streaky sign's direction closely matches the tumor's optimal expansion direction.
  • This finding suggests the streaky sign supports long-distance tumor growth.