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Related Concept Videos

Body Temperature01:25

Body Temperature

941
The body's temperature, measured in degrees, is determined by the balance between heat production and dissipation to the surrounding environment. For instance, if exercising vigorously, the body will produce more heat, causing sweat and dissipating that heat. Despite extreme environmental conditions and physical exertion, the human temperature-control system maintains a constant core body temperature (the temperature of deep tissues, which are the tissues located beneath the skin and other...
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Thermosensation01:43

Thermosensation

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Peripheral thermosensation is the perception of external temperature. A change in temperature (on the surface of the skin and other tissues) is detected by a family of temperature-sensitive ion channels called Transient Receptor Potential, or TRP, receptors. These receptors are located on free nerve endings. Those detecting cold temperatures are closer to the surface of the skin than the nerve endings detecting warmth. These thermoTRP channels, while temperature selective, have relatively...
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Thermoregulation01:26

Thermoregulation

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The human body has a sophisticated thermoregulation system that employs negative feedback mechanisms to maintain an optimal core temperature. When the core temperature drops, peripheral and central thermoreceptors send signals to the hypothalamus, activating the heat-promoting center. This center triggers several responses aimed at increasing the core temperature. First, vasoconstriction reduces the flow of warm blood from internal organs to the skin so that the heat is not lost from the skin,...
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Decreased Body Temperature01:29

Decreased Body Temperature

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A decreased body temperature can occur in patients with hypothermia and frostbite. Heat loss with extended cold exposure overpowers the body's ability to create heat, resulting in hypothermia. Core temperature readings help classify hypothermia. Mild hypothermia is temperatures between 32 °C (89.6 °F) and 35°C (95 °F) and is caused by impaired thermoregulation. Moderate hypothermia is temperatures between 28 C (82.4 °F) and 32 °C (89.6 °F) caused by...
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Field-Based Thermal Physiology Assay: Cold Shock Recovery under Ambient Conditions
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Vertebrate behavioral thermoregulation: knowledge and future directions.

Bradley Cutler1,2, Martin Haesemeyer2

  • 1Graduate program in Molecular, Cellular and Developmental Biology, Columbus, Ohio, United States.

Neurophotonics
|May 21, 2024
PubMed
Summary

Understanding animal thermoregulation is vital. This review summarizes current knowledge on neural control of body temperature and identifies future research directions, especially for behavioral thermoregulation, advocating a neuro-computational approach.

Keywords:
behaviorcircuitscomputationhomeostasisimagingthermoregulation

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Area of Science:

  • Neuroscience
  • Physiology
  • Computational Biology

Background:

  • Thermoregulation is essential for animal survival, involving neural detection of temperature and integration with internal states.
  • Recent advances have identified key molecules and neural pathways governing thermoregulation.
  • Significant knowledge gaps persist, particularly concerning behavioral thermoregulation.

Purpose of the Study:

  • To review the current state of research on animal thermoregulation.
  • To highlight existing knowledge and identify critical areas for future investigation.
  • To propose a neuro-computational perspective for understanding thermoregulatory mechanisms.

Main Methods:

  • Literature review and synthesis of existing research findings.
  • Identification of key molecular and neural circuit components.
  • Analysis of current challenges and future research opportunities.

Main Results:

  • Summary of identified molecules and neural pathways controlling thermoregulation.
  • Highlighting of open questions, especially in behavioral thermoregulation.
  • Emphasis on the need for a neuro-computational approach.

Conclusions:

  • The field has identified crucial elements of thermoregulatory control.
  • Further research is needed to fully understand behavioral thermoregulation.
  • A neuro-computational framework is proposed as a future direction, enabled by advanced tools and modeling.