Related Experiment Video
Updated: Jun 25, 2025

Robotic Myotomy and Partial Fundoplication for Achalasia
Published on: August 11, 2023
Generalized megaesophagus associated with Schmidt-like syndrome in a dog
Reza Azargoun1, Seyed Mohammad Hashemi-Asl2, Siamak Asri-Rezaei1
1Department of Internal Medicine and Clinical Pathology, Faculty of Veterinary Medicine, Urmia University, Urmia, Iran.
This case study highlights a rare autoimmune polyglandular syndrome (APS) in a dog, presenting with megaesophagus. Successful treatment of concurrent hypothyroidism, hypoadrenocorticism, and myasthenia gravis resolved the megaesophagus.
Area of Science:
- Veterinary Medicine
- Endocrinology
- Immunology
Background:
- Megaesophagus in dogs can stem from various underlying conditions.
- Autoimmune polyglandular syndromes (APS) are rare, complex endocrine-autoimmune disorders.
- Schmidt's syndrome, a form of APS, involves adrenal insufficiency and autoimmune thyroid disease.
Related Concept Videos
Barrett Esophagus-I: Introduction
This constant acid exposure transforms the esophagus's pink mucosal lining (stratified squamous epithelium) into a type of lining more...
Barrett Esophagus-II: Clinical Manifestations and Management
To diagnose Barrett's esophagus, healthcare providers often recommend an endoscopy for those showing symptoms of acid reflux. The procedure...
Esophageal Strictures-I: Introduction
Etiology
The primary cause of esophageal strictures is long-standing gastroesophageal reflux disease (GERD), accounting for about 70 to 80% of adult cases. Chronic acid reflux can lead to injury and scarring of the esophageal lining, culminating in...
Esophageal Strictures-II: Clinical Features and Management
Healthcare providers should gather a comprehensive medical history and conduct a physical examination for diagnosis. If esophageal stricture is...
Gastroesophageal Reflux Disease I: Meaning and Pathophysiology
Gastroesophageal Reflux Disease II: Clinical Features and Management
Clinical Manifestations
GERD presents itself in a multitude of ways, with symptoms varying from person to person. The hallmark symptoms are...

