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Radiopathologic findings of multifocal nodular hepatic steatosis
Mouhamed Diop1, Sandeep Sharma1,2, Michael Samuel1
1Division of Interventional Radiology, Department of Radiology, University of Cincinnati, Cincinnati, OH, USA.
Radiology Case Reports
|May 21, 2024
Summary
Multifocal nodular hepatic steatosis (MFNHS) can mimic cancer metastasis on imaging. Magnetic resonance imaging (MRI) is effective in diagnosing MFNHS, with most patients showing stable or improved conditions.
Area of Science:
- Radiology
- Hepatology
- Pathology
Background:
- Multifocal nodular hepatic steatosis (MFNHS) is a rare condition.
- MFNHS can present as multiple liver lesions, mimicking metastatic disease.
- Accurate diagnosis is crucial to avoid unnecessary invasive procedures.
Observation:
- This retrospective study reviewed 10 patients diagnosed with MFNHS between 2005 and 2023.
- Patients presented with suspicious liver lesions on ultrasound (US) or computed tomography (CT).
- Magnetic resonance imaging (MRI) and image-guided biopsy were utilized for diagnosis.
Findings:
- All patients initially had lesions suspicious for malignancy.
- Histopathology confirmed hepatic steatosis in biopsied cases.
- Follow-up showed 71.5% of patients remained stable or improved; 28.5% progressed.
Implications:
- MRI is a reliable tool for detecting and characterizing MFNHS.
- MRI can help differentiate MFNHS from metastatic disease.
- Consider MRI for evaluating multiple hepatic lesions when metastatic suspicion is low.
