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Updated: Jun 25, 2025

Imaging of In Situ Interferon Gamma Production in the Mouse Spleen following Listeria monocytogenes Infection
Published on: July 16, 2019
Disseminated mycobacterium avium complex spinal osteomyelitis in a patient with interferon gamma receptor deficiency:
Sarah Jaggernauth1, Andrew Waack1, Alastair Hoyt2
1University of Toledo College of Medicine and Life Sciences, Toledo, OH 43614, USA.
Abstract:
Disseminated mycobacterium avium complex (MAC) infection is rare and is classically associated with immunodeficient states. Osteomyelitis is a rare manifestation of disseminated MAC infection. The overwhelming majority of MAC infections occur in patients with human immunodeficiency virus (HIV). Disseminated MAC infection has been described in interferon gamma receptor deficiency, an immunodeficiency mechanistically linked to mycobacterial infection. We present a case of disseminated MAC vertebral osteomyelitis in a patient with interferon gamma receptor deficiency.
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