Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Angle Closure Glaucoma: Treatment01:28

Angle Closure Glaucoma: Treatment

479
Angle-closure glaucoma, or closed-angle glaucoma, is an eye condition where the iris bulges out and blocks the iridocorneal angle, resulting in a buildup of aqueous humor and increased intraocular pressure. Immediate medical attention is necessary due to the sudden onset of symptoms. The treatment for angle-closure glaucoma includes short-term and long-term approaches. Short-term treatment involves using eye drops like pilocarpine to lower intraocular pressure by increasing aqueous humor...
479
Open Angle Glaucoma: Treatment01:27

Open Angle Glaucoma: Treatment

430
In open-angle glaucoma, the iridocorneal angle remains open, but the trabecular meshwork becomes stiff, slowing down the outflow of aqueous humor. This causes a buildup of aqueous humor in the anterior chamber, leading to a sudden increase in intraocular pressure. The treatment for open-angle glaucoma focuses on reducing the elevated intraocular pressure by either decreasing the secretion of aqueous humor or increasing its outflow.
Drugs such as carbonic anhydrase inhibitors, α2- and...
430
Glaucoma: Overview01:25

Glaucoma: Overview

548
Glaucoma is an eye condition characterized by increased intraocular pressure that damages the retina and optic nerve, leading to irreversible blindness if left untreated. The human eye has various components, including the cornea, iris, pupil, lens, and optic nerve. Aqueous humor is secreted by the epithelium of the ciliary body in the posterior chamber and flows through the trabecular meshwork and canal of Schlemm, maintaining normal intraocular pressure. The trabecular meshwork and the canal...
548

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Topiramate's ocular trap: acute angle closure rescued by early systemic steroid therapy.

BMJ case reports·2026
Same author

Pb (II) Biosorption by Ramalina conduplicans Biomass: Adsorption Behavior and Binding Mechanisms.

Water environment research : a research publication of the Water Environment Federation·2026
Same author

Evaluating the Correlation Between Optical Coherence Tomography Angiography-Derived Parameters and Serum Vascular Endothelial Growth Factor-A (VEGF-A) Levels in Central Serous Chorioretinopathy.

Cureus·2026
Same author

High dose versus low dose Mitomycin-C assisted bleb needling in failing trabeculectomy blebs: a prospective comparative study.

International ophthalmology·2026
Same author

Electricity-driven sustainable synthesis of 2-aminobenzonitriles through C-C bond cleavage of isatins: post-functionalization <i>via</i> one-pot integration with enzyme catalysis.

Organic & biomolecular chemistry·2026
Same author

Green-synthesized silver-alginate-ciprofloxacin hydrogel: A multifaceted therapeutic for enhanced diabetic and burn Wound healing.

Journal of biomaterials applications·2026
Same journal

Eye injury rates and community cost savings through vision centers: Evidence from southern India.

Indian journal of ophthalmology·2026
Same journal

Evaluation of the protective efficiency of polycarbonate goggles against firecracker-related ocular injuries.

Indian journal of ophthalmology·2026
Same journal

Comment on: Clinical characteristics, risk factor analysis, and outcomes of graft rejection after Descemet membrane endothelial keratoplasty.

Indian journal of ophthalmology·2026
Same journal

Issue regarding E Log book for PG students: Paper to pixels.

Indian journal of ophthalmology·2026
Same journal

Methylation matters: A case control study on epigenetic alteration in diabetic retinopathy.

Indian journal of ophthalmology·2026
Same journal

Understanding the disconnect: A pilot study of public perception versus reality of corneal donation in India.

Indian journal of ophthalmology·2026
See all related articles

Related Experiment Video

Updated: Jun 25, 2025

Ultrasound Cyclo Plasty in Eyes with Glaucoma
05:05

Ultrasound Cyclo Plasty in Eyes with Glaucoma

Published on: January 26, 2018

12.2K

Phacoemulsification in angle-closure glaucoma: A 360° evaluation.

Kirti Singh1, Himshikha Aggarwal2, Mainak Bhattacharyya3

  • 1Director and Professor, Department of Ophthalmology, Guru Nanak Eye Centre, New Delhi, India.

Indian Journal of Ophthalmology
|May 21, 2024
PubMed
Summary
This summary is machine-generated.

Phacoemulsification significantly reduces intraocular pressure (IOP) and widens anterior chamber angles (ACA) in primary angle-closure glaucoma (PACG) patients with cataracts. This early intervention improves aqueous outflow and disease management.

More Related Videos

Full-Circle Cauterization of Limbal Vascular Plexus for Surgically Induced Glaucoma in Rodents
10:10

Full-Circle Cauterization of Limbal Vascular Plexus for Surgically Induced Glaucoma in Rodents

Published on: February 15, 2022

1.4K
Iris Fixation via External Pentagram Suturing
05:22

Iris Fixation via External Pentagram Suturing

Published on: May 5, 2022

1.3K

Related Experiment Videos

Last Updated: Jun 25, 2025

Ultrasound Cyclo Plasty in Eyes with Glaucoma
05:05

Ultrasound Cyclo Plasty in Eyes with Glaucoma

Published on: January 26, 2018

12.2K
Full-Circle Cauterization of Limbal Vascular Plexus for Surgically Induced Glaucoma in Rodents
10:10

Full-Circle Cauterization of Limbal Vascular Plexus for Surgically Induced Glaucoma in Rodents

Published on: February 15, 2022

1.4K
Iris Fixation via External Pentagram Suturing
05:22

Iris Fixation via External Pentagram Suturing

Published on: May 5, 2022

1.3K

Area of Science:

  • Ophthalmology
  • Glaucoma Research
  • Surgical Innovation

Background:

  • Primary angle-closure glaucoma (PACG) poses a significant risk to vision.
  • Cataracts can exacerbate intraocular pressure (IOP) and complicate PACG management.
  • Phacoemulsification is a common cataract surgery technique.

Purpose of the Study:

  • To assess the impact of phacoemulsification on IOP and anterior chamber angle (ACA) morphology in PACG patients.
  • To evaluate the efficacy of cataract surgery in managing PACG.
  • To determine if phacoemulsification aids in controlling disease progression.

Main Methods:

  • A prospective, hospital-based study involving 40 PAC and PACG eyes with visually significant cataracts.
  • Patients underwent phacoemulsification.
  • Evaluations included IOP, ACA widening, and disease progression for at least 6 months, with failure defined by elevated IOP or increased medication needs.

Main Results:

  • Phacoemulsification led to a statistically significant IOP reduction (P < 0.0001) of 42.2% over 6 months (mean 8.9 ± 3.59 mmHg).
  • The need for antiglaucoma medications (AGMs) decreased dramatically, from 39/40 patients preoperatively to 1/38 postoperatively.
  • Success was achieved in 95% of cases, with documented angle widening and no progression in disc damage or visual fields.

Conclusions:

  • Early cataract surgery (phacoemulsification) is effective in controlling IOP and PACG progression.
  • The procedure widens angles, improves aqueous outflow, and enhances visual acuity.
  • Phacoemulsification facilitates better disease monitoring and reduces the long-term economic burden of glaucoma management.