Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Bone Marrow Sampling and Transplants

Bone Marrow Sampling and Transplants

Bone marrow transplant is a potential cure for several diseases, including cancer and specific genetic disorders. Notably, this procedure is applicable for patients suffering from aplastic anemia, certain types of leukemia, severe combined immunodeficiency disease (SCID), Hodgkin's disease, non-Hodgkin's lymphoma, multiple myeloma, thalassemia, sickle-cell disease, and certain cancers.
The transplant begins with high doses of chemotherapy and radiation treatment, which aim to destroy...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

The relationship between frailty and cirrhosis etiology: From the Functional Assessment in Liver Transplantation (FrAILT) Study.

Liver international : official journal of the International Association for the Study of the Liver·2021

Same author

Ambient particulate matter air pollution is associated with increased risk of papillary thyroid cancer.

Surgery·2021

Same author

Implications of defective immune responses in SARS-CoV-2 vaccinated organ transplant recipients.

Science immunology·2021

Same author

The benefit to waitlist patients in a national paired kidney exchange program: Exploring characteristics of chain end living donor transplants.

American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons·2021

Same author

Correcting the sex disparity in MELD-Na.

American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons·2021

Same author

Quantifying The Costs of Creating and Maintaining Hemodialysis Access in An All-Payer Rate-Controlled Health System.

Annals of vascular surgery·2021

Same journal

Filtered or Fried? Rethinking Intraoperative Cell Salvage in Liver Transplantation.

Transplantation·2026

Same journal

Simultaneous Liver-kidney Versus Liver Transplantation Categorized by Pretransplant eGFR: Impact of the 2017 OPTN Policy.

Transplantation·2026

Same journal

Preformed Anti-DQ Alpha Donor-specific Antibodies and the Risk of Antibody-mediated Rejection After Kidney Transplantation.

Transplantation·2026

Same journal

People in Transplantation: Professor Nadey Hakim, MD, PhD, FRCS, FRCSGlas (Hon), FACS, President-Elect of The Transplantation Society.

Transplantation·2026

Same journal

IL-1 Receptor Blockade Modulates Inflammation During Sequential Perfusion in Ex Vivo Porcine Kidneys.

Transplantation·2026

Same journal

Regulatory T Cells Allosensitized Under the Blockade of CD80/CD86-CD28 Costimulation Prolonged Islet Allograft Survival.

Transplantation·2026

See all related articles

Search research articles

Related Experiment Video

Updated: Jun 25, 2025

Mouse Kidney Transplantation: Models of Allograft Rejection

Mouse Kidney Transplantation: Models of Allograft Rejection

Published on: October 11, 2014

Differences in Racial and Ethnic Disparities Between First and Repeat Kidney Transplantation.

Shaifali Sandal^1,2,3, JiYoon Ahn⁴, Yusi Chen⁵

¹Division of Nephrology, Department of Medicine, McGill University Health Centre, Montreal, QC, Canada.

Transplantation

|May 21, 2024

Summary

This summary is machine-generated.

Racial and ethnic disparities in kidney transplantation access are greater for repeat transplants than for first-time transplants. Black and Hispanic patients with graft failure do not benefit from repeat kidney transplants, indicating persistent systemic barriers.

More Related Videos

A Modified Surgical Technique for Kidney Transplantation in Mice

A Modified Surgical Technique for Kidney Transplantation in Mice

Published on: July 22, 2022

Murine Kidney Transplant Technique

Murine Kidney Transplant Technique

Published on: October 20, 2015

Related Experiment Videos

Last Updated: Jun 25, 2025

Mouse Kidney Transplantation: Models of Allograft Rejection

Mouse Kidney Transplantation: Models of Allograft Rejection

Published on: October 11, 2014

A Modified Surgical Technique for Kidney Transplantation in Mice

A Modified Surgical Technique for Kidney Transplantation in Mice

Published on: July 22, 2022

Murine Kidney Transplant Technique

Murine Kidney Transplant Technique

Published on: October 20, 2015

Area of Science:

Nephrology
Transplantation
Health Equity

Background:

Patients with graft failure may have better access to repeat kidney transplantation (re-KT) than transplant-naive patients accessing first KT.
It is unknown if this potential advantage is equitably distributed across racial and ethnic groups.
This study aimed to compare racial/ethnic disparities in access to re-KT versus first KT.

Purpose of the Study:

To compare the magnitude of racial/ethnic disparities in access to repeat kidney transplantation (re-KT) versus first kidney transplantation (first KT).
To investigate whether the previously observed advantage in re-KT access for patients with graft failure is equitably distributed.
To identify persistent systemic barriers affecting transplant equity.

Main Methods:

Utilized the United States Renal Data System (USRDS) from 1995 to 2018.
Included 104,454 White, Black, and Hispanic patients with graft failure and 2,357,753 transplant-naive dialysis patients.
Employed adjusted Cox regression to estimate disparities in access to first and re-KT, and used a Wald test to compare disparity magnitudes.

Main Results:

Black patients faced inferior access to waitlisting and receiving both first KT and re-KT.
Racial/ethnic disparities in waitlisting and receiving re-KT were greater than for first KT (Pinteraction < 0.001 for receiving).
Hispanic patients showed greater disparities in waitlisting for re-KT compared to first KT, but similar disparities in receiving re-KT versus first KT.

Conclusions:

Unlike White patients, Black and Hispanic patients with graft failure do not experience improved access to repeat kidney transplantation.
These findings suggest that structural and systemic barriers persist for racialized patients seeking re-KT.
Systemic changes are necessary to achieve equitable access to kidney transplantation for all patients.