Machine learning and artificial intelligence within pediatric autoimmune diseases: applications, challenges, future

Parniyan Sadeghi1,2, Hanie Karimi1,3, Atiye Lavafian1,4

  • 1Network of Interdisciplinarity in Neonates and Infants (NINI), Universal Scientific Education and Research Network (USERN), Tehran, Iran.

Insights

Machine learning aids in diagnosing and managing pediatric autoimmune diseases, offering improved precision and personalized treatments. This technology helps identify new biomarkers and therapeutic targets for better patient outcomes.

Area of Science:

  • Pediatric autoimmune diseases
  • Medical informatics
  • Machine learning applications

Background:

  • Autoimmune disorders impact 4.5%–9.4% of children, affecting quality of life.
  • Diagnosis and prognosis are challenging due to varied disease presentation.
  • Machine learning (ML) offers pattern recognition from large datasets for improved patient management.

Purpose of the Study:

  • To review current knowledge on ML applications in pediatric autoimmune diseases.
  • To identify gaps in the existing research and applications of ML.
  • To explore the transformative potential of ML in pediatric autoimmune care.

Main Methods:

  • Narrative review methodology.
  • Extensive literature search across PubMed, Scopus, and Web of Science.
  • Focus on ML applications in pediatric autoimmune and related conditions.

Main Results:

  • ML algorithms can enhance diagnostic accuracy and speed in pediatric autoimmune disorders.
  • ML facilitates the identification of novel biomarkers and therapeutic targets.
  • Personalized treatment strategies can be developed using ML-driven analytics.

Conclusions:

  • ML holds significant potential to revolutionize the identification, treatment, and management of pediatric autoimmune diseases.
  • Physicians can leverage ML for more precise clinical judgments and tailored patient care.
  • Further research is needed to fully integrate ML into pediatric autoimmune disease management.
Abstract