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Putting Methylphenidate for Cancer-Related Fatigue to Rest?

Nicolas Chin-Yee1,2, Sriram Yennurajalingam3, Camilla Zimmermann1,2

  • 1Department of Supportive Care, Princess Margaret Cancer Centre, University Health Network, Toronto, Canada.

Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology
|May 21, 2024
PubMed
Abstract

No abstract available in PubMed .

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Dopamine receptor antagonists, also known as antipsychotic agents, are critical in managing chemotherapy-induced vomiting. These antiemetic agents block dopamine receptors in the chemoreceptor trigger zone (CTZ), inhibiting signal transmission to the vomiting center. Antipsychotic agents encompass phenothiazines (PTZ), butyrophenones, benzamides, and thienobenzodiazepines (Zyprexa), which are utilized for their antiemetic and sedative properties.
Phenothiazines, such as prochlorperazine...
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