Related Experiment Video
Updated: Jun 25, 2025

Using a Murine Model of Psychosocial Stress in Pregnancy as a Translationally Relevant Paradigm for Psychiatric Disorders in Mothers and Infants
Published on: June 13, 2021
Maternal suicide risk predicts preschooler emotional and behavioral problems
Maureen Zalewski1, Amy L Byrd2, Vera Vine3
1University of Oregon, Eugene, OR 97403, USA.
Maternal history of suicidal thoughts and behaviors (STBs) is linked to increased negative affect and aggressive behavior in preschoolers. This research highlights early risk factors for intergenerational suicide risk.
Area of Science:
- Psychiatry
- Developmental Psychology
- Child Psychology
Background:
- Maternal history of suicidal thoughts and behaviors (STBs) is a significant risk factor for offspring emotional and behavioral issues.
- Prior research primarily focused on adolescent and adult samples, necessitating examination of early childhood risk correlates.
- Understanding early indicators is crucial for intervening before STBs emerge in children.
Purpose of the Study:
- To investigate the association between maternal history of STBs and emotional/behavioral correlates in preschoolers.
- To examine negative affect, internalizing problems, attention problems, and aggressive behavior as correlates.
- To extend prior work by focusing on the preschool period.
Main Methods:
- A sample of 158 mother-preschooler dyads was studied.
- Maternal history of STBs was assessed, with approximately 50% endorsing such a history.
- Preschooler behaviors (negative affect, aggression) were reported by mothers and teachers.
Main Results:
- Maternal history of STBs was significantly associated with increased aggressive behavior in preschoolers, based on both mother and teacher reports.
- A significant association was found between maternal STB history and preschoolers' negative affect, as reported by mothers.
- 20% of the sample scored at a threshold indicating potential suicide risk.
Conclusions:
- Maternal STB history is linked to heightened negative affect and aggressive behavior in preschoolers.
- These findings support the role of early childhood behaviors in models of intergenerational suicide risk transmission.
- Early identification of these correlates can inform preventative strategies for at-risk children.
Related Concept Videos
Socioemotional Development during Infancy
Primary Temperament Types
Psychological and Sociocultural Causes of Schizophrenia
Stress and Mental Health
Individuals with depression often experience challenges in both their personal and professional...
Parenting Styles
Authoritarian Parenting
This style is strict and controlling, with little room for open dialogue. Authoritarian parents demand obedience and often enforce rules with minimal warmth. Children raised this way may lack social skills and initiative, usually comparing themselves to others unfavorably.
Authoritative...
Depressive Disorders: Etiology
Biological Factors in Depression
Biological predispositions significantly influence the risk of developing depressive disorders. Genetic studies highlight the role of variations in the serotonin transporter...
Attention-Deficit/Hyperactivity Disorder
Diagnostic Criteria and Symptoms
To diagnose ADHD, symptoms must manifest before age 12 and be evident across multiple settings....

