Racial/ethnic trends in opioid and polysubstance opioid overdose mortality in adolescents and young adults, 1999-2020
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View abstract on PubMed
Summary
This summary is machine-generated.Opioid overdose deaths rose across all races in young people. Non-Hispanic Black adolescents and young adults saw the steepest increases in opioid and opioid-stimulant overdose mortality.
Area Of Science
- Public Health
- Epidemiology
- Toxicology
Background
- Opioid overdose mortalities exhibit disparities across racial and ethnic groups.
- Adolescents and young adults represent a critical demographic for understanding overdose trends.
Purpose Of The Study
- To analyze racial/ethnic trends in opioid and polysubstance opioid overdose mortalities.
- To characterize differences and identify potential sub-epidemics within adolescent and young adult populations.
Main Methods
- Utilized U.S. Centers for Disease Control and Prevention (CDC) Wide-Ranging Online Data for Epidemiologic Research (WONDER) mortality data (1999-2020).
- Identified drug overdose mortalities using International Classification of Diseases, Tenth Revision (ICD-10) codes.
- Employed Joinpoint regression to analyze mortality rates for opioids and polysubstance combinations across racial/ethnic groups in adolescents and young adults.
Main Results
- Average Annual Percent Change (AAPC) in mortality due to opioid and polysubstance opioid overdose increased for all analyzed racial/ethnic groups (1999-2020).
- The highest AAPC for mortality involving any opioid and opioids with a stimulant was observed in non-Hispanic Black individuals.
- Significant increases in opioid-stimulant overdose mortality emerged around 2012.
Conclusions
- Opioid overdose mortality has seen unprecedented increases in adolescents and young adults over the past two decades.
- The opioid overdose epidemic's "waves" may not uniformly apply across all racial/ethnic groups due to heterogeneous trends.
- The rise in opioid-stimulant overdose mortality highlights the complex interplay of the third and fourth waves of the crisis.
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