Prostate cancer across four countries in the Middle East: a multi-centre, observational, retrospective and prognostic study
These videos have been matched automatically. Contact us if they are not relevant.
These videos have been matched automatically. Contact us if they are not relevant.
View abstract on PubMed
Summary
This summary is machine-generated.This study highlights a lack of prostate cancer (PC) awareness in the Middle East, with many patients diagnosed at advanced stages. There is a critical need for novel treatments due to common disease progression in metastatic PC.
Area Of Science
- Oncology
- Urology
- Public Health
Background
- Prostate cancer (PC) is the second most common cancer in men globally.
- Incidence of PC is increasing in the Middle East (ME).
- Real-world data on PC patient characteristics and treatment in the ME is limited.
Purpose Of The Study
- To collect real-world data on PC patient characteristics in the ME.
- To analyze disease progression patterns in ME PC patients.
- To evaluate treatment strategies and outcomes for PC in the ME.
Main Methods
- Retrospective, observational, multi-center study.
- Data from 615 male PC patients across 10 centers in Lebanon, Saudi Arabia, Iraq, and Kuwait.
- Analysis of medical records from January 2012 to December 2018/May 2019.
Main Results
- Most patients presented with localized/locally advanced PC (57.7%) or metastatic castration-sensitive PC (mCSPC) (37.4%).
- High proportion of patients at advanced TNM stages (IIIa: 40.1%, IVb: 27.8%) at diagnosis.
- Median time to metastatic disease was 84 months; disease progression common in mCSPC (35.1%) and metastatic castration-resistant PC (mCRPC) (14.8%).
Conclusions
- Advanced TNM stage at diagnosis suggests low PC awareness in the ME.
- Disease progression in metastatic PC highlights challenges in treatment.
- Urgent need for novel therapeutic strategies for advanced and metastatic PC in the region.
These videos have been matched automatically. Contact us if they are not relevant.
These videos have been matched automatically. Contact us if they are not relevant.
