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Updated: Jun 25, 2025

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Endoscopic Bilateral Nipple-sparing Mastectomy via a Single Axillary Incision with Immediate Pre-pectoral Implant-based Breast Reconstruction
Published on: May 17, 2024
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Immediate Prepectoral Tissue Expander Breast Reconstruction Without Acellular Dermal Matrix Is Equally Safe Following
Nader Henry1, Victoria Sebag2, Tyler Safran1
1From the Division of Plastic and Reconstructive Surgery, McGill University Health Centre, Montreal, Quebec, Canada.
Annals of Plastic Surgery
|May 22, 2024
Summary
Immediate breast reconstruction using tissue expanders without acellular dermal matrix (ADM) shows similar outcomes for nipple-sparing mastectomy (NSM) and skin-sparing mastectomy (SSM) patients. This approach offers cost savings without compromising safety.
Area of Science:
- Plastic Surgery
- Breast Reconstruction Techniques
- Oncologic Surgery Outcomes
Background:
- Prepectoral breast reconstruction is gaining popularity.
- Limited data exists on mastectomy type impact in prepectoral reconstruction without acellular dermal matrix (ADM).
- Tissue expander use in prepectoral reconstruction is a key focus.
Purpose of the Study:
- Compare 90-day surgical outcomes of prepectoral tissue expander reconstruction.
- Evaluate outcomes between nipple-sparing mastectomy (NSM) and skin-sparing mastectomy (SSM).
- Assess complication rates in immediate prepectoral reconstruction without ADM.
Main Methods:
- Retrospective review of 79 patients (97 breasts) from June 2020 to December 2021.
- Included patients undergoing NSM or SSM with immediate prepectoral tissue expander reconstruction without ADM.
- Complications were recorded, categorized, and statistically analyzed.
Main Results:
- Overall complication rate was 22.7% (22 of 97 breasts).
- No statistically significant difference in total complications between NSM (25.7%) and SSM (21.0%) groups.
- Incidence of major and minor complications did not differ significantly between groups.
Conclusions:
- Tissue expander breast reconstruction without ADM yields similar outcomes for NSM and SSM.
- No significant differences in complication rates were observed between the mastectomy types.
- Reconstruction without ADM provides institutional cost savings without compromising patient safety.

