Development of Aloe vera-titanium oxide-based ultrasensitive sensor for the quantification of quercetin

In the present work, a novel sensor developed for the quantification of quercetin (QRC) is being reported. Due to synergistic effects of Aloe vera and titanium oxide, voltammetric performance of the developed sensor (ALV-TiO₂/glassy carbon electrode) was greatly enhanced. The fabricated sensor was characterized by scanning electron microscopy, X-ray diffraction, energy dispersive X-ray, and electrochemical impedance spectroscopy. The sensor was applied to study electrochemical behavior of QRC using square wave voltammetry. Under optimal condition, the developed sensor exhibited a linear response in the range of 3.3 × 10^-7 to 2.31 × 10^-6 µM with a detection limit of 0.8 nM. The analytical utility of the proposed sensor was justified by applying it for the analysis of QRC in real samples.