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Updated: Jun 25, 2025

Infecting Mice with Malassezia spp. to Study the Fungus-Host Interaction
Published on: November 6, 2019
Malassezia-associated skin diseases in the pediatric population
Christy H Chang1, Sarah L Stein2
1College of Medicine, University of Illinois Chicago, Chicago, Illinois, USA.
Abstract:
Malassezia are yeast species that commonly colonize healthy skin. However, they have been associated with or implicated in the pathogenesis of numerous skin disorders, particularly in the setting of pediatric populations. In this review, we will focus on several Malassezia-associated skin conditions manifesting in infants, children, and adolescents: pityriasis versicolor, Malassezia folliculitis, infantile and adolescent seborrheic dermatitis, head and neck dermatitis, and neonatal cephalic pustulosis. We examine the literature and provide an overview of these conditions, including clinical presentation in diverse skin colors, diagnosis, risk factors, and treatment and management. Additionally, we summarize and highlight some of the proposed theories on the role of Malassezia spp. in the pathogenesis of these skin conditions.
Insights
Malassezia yeasts are linked to pediatric skin issues like seborrheic dermatitis and pityriasis versicolor. This review covers their role in infant and adolescent skin conditions, including diagnosis and management.
Area of Science:
- Dermatology
- Mycology
- Pediatrics
Background:
- Malassezia yeasts are common skin commensals.
- These yeasts are implicated in various pediatric skin disorders.
- Focus on conditions in infants, children, and adolescents.
Purpose of the Study:
- To review Malassezia-associated skin conditions in pediatric populations.
- To provide an overview of clinical presentation, diagnosis, risk factors, and management.
- To summarize proposed pathogenic roles of Malassezia species.
Main Methods:
- Literature review of Malassezia-associated skin conditions.
- Analysis of clinical presentations across diverse skin tones.
- Examination of diagnostic and therapeutic strategies.
Main Results:
- Identified key pediatric Malassezia-related conditions: pityriasis versicolor, folliculitis, seborrheic dermatitis, head and neck dermatitis, and neonatal cephalic pustulosis.
- Detailed clinical features, diagnostic approaches, and management options.
- Explored theories on Malassezia's role in disease pathogenesis.
Conclusions:
- Malassezia yeasts play a significant role in several pediatric dermatoses.
- Comprehensive understanding of these conditions is crucial for effective diagnosis and treatment in children.
- Further research into Malassezia pathogenesis is warranted.
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