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Residual Renal Function: A Double-Edged Sword
Sandra Karanović Štambuk1,2, Margareta Fištrek-Prlić1, Bojan Jelaković1,2
1Division of Nephrology, Arterial Hypertension, Dialysis and Transplantation, Department of Internal Medicine, University Hospital Zagreb, Zagreb, Croatia.
Introduction:
Nephrotic syndrome may persist despite end-stage kidney disease and result in dyslipidaemia, thrombosis and a significantly increased cardiovascular risk. Treatment of refractory nephrotic syndrome includes surgical bilateral nephrectomy, renal artery embolization and pharmacologic nephrectomy.
Case Presentation:
We present a case of a haemodialysis patient with refractory nephrotic syndrome who underwent pharmacologic nephrectomy. The procedure decreased the patient's cardiovascular risk and enabled the patient to become a candidate for kidney transplantation.
Conclusion:
In certain situations residual renal function may be harmful. In such instances, nephrectomy should be considered. Pharmacologic nephrectomy using nephrotoxic drugs is a non-invasive approach with least potential complications.
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