Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

A chromosome-level genome assembly of Neotoxoptera formosana (Takahashi, 1921) (Hemiptera: Aphididae).

G3 (Bethesda, Md.)·2022
Same author

Genetic encoding of an esophageal motor circuit.

Cell reports·2022
Same author

Stress Monitoring of Concrete via Uniaxial Piezoelectric Sensor.

Sensors (Basel, Switzerland)·2022
Same author

Resolving mutational signatures in cancer development.

Cancer cell·2022
Same author

Catalytic mechanisms underlying fungal fatty acid desaturases activities.

Critical reviews in biotechnology·2022
Same author

Recent developments in horizontal gene transfer with the adaptive innovation of fermented foods.

Critical reviews in food science and nutrition·2022

Related Experiment Video

Updated: Jun 25, 2025

Generation of Alginate Microspheres for Biomedical Applications
10:33

Generation of Alginate Microspheres for Biomedical Applications

Published on: August 12, 2012

20.8K

Microalgae-loaded biocompatible alginate microspheres for tissue repair.

Jinxuan Jia1, Jingping Liu2, Wei Shi1

  • 1State Key Laboratory of Targeting Oncology, National Center for International Research of Bio-targeting Theranostics, Guangxi Key Laboratory of Bio-targeting Theranostics, Collaborative Innovation Center for Targeting Tumor Diagnosis and Therapy, Guangxi Medical University, Nanning, Guangxi, 530021, China.

International Journal of Biological Macromolecules
|May 22, 2024
PubMed
Summary

New microalgae (MA)-loaded alginate hydrogel microspheres promote wound healing. These biocompatible microspheres, enhanced with vascular endothelial growth factor (VEGF), accelerate collagen deposition and vascular generation for effective wound repair.

Keywords:
AlginateMicroalgaeMicrospheresTissue repair

More Related Videos

Author Spotlight: Advancing Therapeutics with Biocompatible Sodium Alginate Hydrogel Microspheres
07:24

Author Spotlight: Advancing Therapeutics with Biocompatible Sodium Alginate Hydrogel Microspheres

Published on: June 7, 2024

1.8K
Synthesis of Thermogelling PolyN-isopropylacrylamide-graft-chondroitin Sulfate Composites with Alginate Microparticles for Tissue Engineering
12:22

Synthesis of Thermogelling PolyN-isopropylacrylamide-graft-chondroitin Sulfate Composites with Alginate Microparticles for Tissue Engineering

Published on: October 26, 2016

11.8K

Related Experiment Videos

Last Updated: Jun 25, 2025

Generation of Alginate Microspheres for Biomedical Applications
10:33

Generation of Alginate Microspheres for Biomedical Applications

Published on: August 12, 2012

20.8K
Author Spotlight: Advancing Therapeutics with Biocompatible Sodium Alginate Hydrogel Microspheres
07:24

Author Spotlight: Advancing Therapeutics with Biocompatible Sodium Alginate Hydrogel Microspheres

Published on: June 7, 2024

1.8K
Synthesis of Thermogelling PolyN-isopropylacrylamide-graft-chondroitin Sulfate Composites with Alginate Microparticles for Tissue Engineering
12:22

Synthesis of Thermogelling PolyN-isopropylacrylamide-graft-chondroitin Sulfate Composites with Alginate Microparticles for Tissue Engineering

Published on: October 26, 2016

11.8K

Area of Science:

  • Biomaterials Science
  • Regenerative Medicine
  • Tissue Engineering

Background:

  • Hydrogel microcarriers are effective for wound repair.
  • Optimizing active microcarriers with natural ingredients is a key research area.
  • Developing adaptable microcarriers for various wound geometries is crucial.

Purpose of the Study:

  • To fabricate and optimize microalgae (MA)-loaded living alginate hydrogel microspheres for enhanced wound healing.
  • To investigate the synergistic effects of MA and vascular endothelial growth factor (VEGF) in wound repair.
  • To assess the efficacy of these novel microcarriers in promoting tissue regeneration.

Main Methods:

  • Fabrication of MA-loaded alginate hydrogel microspheres using microfluidic electrospray technology.
  • Cross-linking of alginate with calcium ions to form stable microspheres.
  • Incorporation of vascular endothelial growth factor (VEGF) into the microspheres.
  • In vivo testing on rat wound models to evaluate healing efficacy.

Main Results:

  • Successfully fabricated stable, biocompatible, MA-loaded living alginate hydrogel microspheres.
  • Demonstrated efficient oxygen release from the microspheres, supporting wound healing.
  • VEGF incorporation significantly enhanced the overall wound treatment effectiveness.
  • MA-VEGF-loaded microspheres promoted collagen deposition and vascular generation in rat wounds.

Conclusions:

  • Microalgae-loaded live alginate hydrogel microspheres offer significant therapeutic value for wound healing.
  • The combination of MA and VEGF in hydrogel microspheres presents a promising strategy for advanced wound care.
  • These findings open new avenues for clinical applications in wound treatment.