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Targeting Megasphaera species to promote cervicovaginal health

Mariano A Molina1, Sneha Biswas2, Virginia Núñez-Samudio3

  • 1Department of Pathology, Vrije Universiteit Amsterdam, Amsterdam UMC location VUmc, Amsterdam, The Netherlands; Cancer Centre Amsterdam, Imaging and Biomarkers, Amsterdam, The Netherlands; Instituto de Ciencias Médicas, Las Tablas, Panamá.

Trends in Microbiology
|May 22, 2024
PubMed

Maintaining a healthy cervicovaginal microbiome (CVM) is vital for women's wellbeing; it is dependent primarily on Lactobacillus dominance. Microbiome imbalances, driven by Megasphaera species, contribute to infections and disease. Comprehensive research into Megasphaera biology and interventions is crucial for personalized women's healthcare, and additional efforts are required to mitigate the risks posed by cervicovaginal dysbiosis.

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