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Development of Gastric Polyps: 15 Years of Proton Pump Inhibitor Therapy
Manuel Cabrera Charleston1, Daniela Guadalupe Oscura Paredes1, Gabriela Alfaro Mendez2
1Internal Medicine, Tecnologico de Monterrey, Monterrey, MEX.
Abstract:
Gastroesophageal reflux disease (GERD) is a common disease affecting millions of people worldwide. Proton pump inhibitors (PPI) are the most common drugs used to treat this acid-related disorder due to their high efficacy and fewer side effects. However, long-term use of these drugs can cause histopathological changes, including cystic dilation of gastric fundic glands. The present report describes a 53-year-old man with chronic GERD and daily use of PPIs 20 mg once a day for over 15 years. This case demonstrates the association between PPI and the development of fundic gland polyps.
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