Complex cystic liver lesions: classification, diagnosis, and management

Area of Science:

• Hepatology
• Gastroenterology
• Radiology

Background:

• Cystic liver disease prevalence ranges from 15-18%, often detected incidentally.
• Complex cystic liver lesions represent a diverse group, from non-neoplastic to malignant conditions.
• Clinicopathological features and oncogenic pathways of these lesions are not fully understood.

Purpose of the Study:

• To provide an updated overview of the diagnosis, classification, and management of common complex cystic liver lesions.
• To address the diagnostic and therapeutic challenges posed by heterogeneous cystic liver disorders.
• To enhance clinical understanding and improve patient care for complex hepatic cysts.

Main Methods:

• Literature review focusing on recent advancements in imaging modalities.
• Analysis of clinicopathological features and classification systems for cystic liver lesions.
• Synthesis of current management strategies for complex hepatic cysts.

Main Results:

• Improved imaging aids in characterizing and classifying hepatic cysts.
• Complex cystic liver lesions present diagnostic challenges due to overlapping features.
• Accurate diagnosis and management are crucial to reduce morbidity and mortality.

Conclusions:

• A comprehensive understanding of complex cystic liver lesions is essential for effective clinical practice.
• This review offers current insights into the diagnosis, classification, and management of these challenging conditions.
• Timely and accurate intervention can significantly improve outcomes for patients with cystic liver disease.