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Gastroschisis and septo-optic-pituitary dysplasia: Is there an association?
Michael S Salman1, Chelsea A Ruth2, Marina S Yogendran3
1Section of Pediatric Neurology, University of Manitoba, Winnipeg, Manitoba, Canada.
Aim:
There are several case reports describing patients with both optic nerve hypoplasia/septo-optic-pituitary dysplasia (ONH/SOD) and gastroschisis (GS). Our aim was to investigate whether ONH/SOD is associated with GS.
Methods:
A retrospective population-based study was undertaken using the Population Research Data Repository at the Manitoba Center for Health Policy in Manitoba, Canada to investigate if any patient with ONH/SOD also had GS. In addition, Winnipeg's Surgical Database of Outcomes and Management (WiSDOM), a hospital-based paediatric surgical database, was searched to ascertain if any of the patients with GS also have ONH/SOD.
Results:
Cases were 124 patients with ONH/SOD diagnosed during 1990-2019. None had GS. The surgical database had 188 patients from Manitoba with GS during 1991-2019. None had ONH/SOD.
Conclusion:
There does not appear to be an association between ONH/SOD and GS in our cohorts of patients with these two disorders.
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