In-bore MRI targeted biopsy. Lights and shadows

Area of Science:

• Urology
• Radiology
• Oncology

Background:

• Multiparametric Magnetic Resonance Imaging (MpMRI) and MRI-guided biopsy (MRGB) are the current gold standard for diagnosing prostate cancer (PCa).
• Existing research lacks direct comparisons between Transrectal Ultrasound MRI-guided Biopsy (TRUS-MRGB), Cognitive Fusion Biopsy (COG-TB), and In-Bore MRI-guided Biopsy (IB-MRGB).

Purpose of the Study:

• To compare the diagnostic accuracy and effectiveness of different prostate cancer biopsy techniques.
• To evaluate the potential advantages and disadvantages of IB-MRGB versus TRUS-MRGB and COG-TB.

Main Methods:

• Review and analysis of studies comparing TRUS-MRGB, COG-TB, and IB-MRGB for prostate cancer detection.
• Assessment of lesion detection rates, operator dependency, and resource implications for each technique.

Main Results:

• IB-MRGB may offer higher accuracy for smaller lesions and reduced operator dependence.
• Concerns remain regarding the high costs associated with IB-MRGB.
• Potential for missed lesions not visible on MRI or detected by systematic biopsy exists with all techniques.

Conclusions:

• Further comparative studies are essential to establish the definitive role of TRUS-MRGB, COG-TB, and IB-MRGB in prostate cancer diagnosis.
• Balancing accuracy, cost, and the risk of missed lesions is crucial when selecting a biopsy method.