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Combination of Microstereolithography and Electrospinning to Produce Membranes Equipped with Niches for Corneal Regeneration

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Intrastromal Corneal Ring Implants Associated Bacterial Infections.

Manjulatha Sara¹, Alex Hui^1,2, Muhammad Yasir¹

¹School of Optometry and Vision Science, UNSW Sydney, Sydney, New South Wales, Australia.

Current Eye Research

|May 23, 2024

Summary

This summary is machine-generated.

Intracorneal Ring Segment (ICRS) implantation can lead to infections, primarily caused by Staphylococcus aureus, often requiring surgical intervention with poor visual outcomes. Research into antimicrobial ICRS is crucial for improving vision restoration.

Keywords:

Ocular implants S. aureus infections intracorneal ring segments microbial keratitis

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Published on: July 22, 2022

Area of Science:

Ophthalmology
Microbiology
Infectious Diseases

Background:

Intracorneal Ring Segment (ICRS) implantation is a surgical procedure for refractive errors and corneal ectatic diseases.
While generally safe, ICRS procedures carry a risk of microbial infections requiring prompt treatment.

Purpose of the Study:

To examine the incidence and resistance patterns of infections associated with Intracorneal Ring Segment (ICRS) implantation.
To identify common pathogens and understand the timing and causes of ICRS-related infections.

Main Methods:

A systematic literature review was conducted using PubMed, Web of Science, and Scopus.
Studies published between January 2000 and December 2022 were included, adhering to PRISMA guidelines.

Main Results:

Gram-positive organisms predominated (86%), with Staphylococcus aureus (35.7%) being the most frequent pathogen.
Early-onset infections are often linked to surgical contamination, while late-onset infections may result from prolonged antibiotic use.
Staphylococcus aureus infections were associated with poorer vision recovery compared to other bacterial infections.

Conclusions:

Staphylococcus aureus is a primary cause of ICRS infections, often necessitating surgical intervention with suboptimal visual results.
Further investigation into antimicrobial ICRS is recommended to enhance vision outcomes.