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A Review of the Use of Intravenous Immunoglobulin Therapy in Dermatology

Casey Engel1, Zachary E Holcomb2

  • 1Virginia Tech-Carilion School of Medicine, Roanoke, VA, USA.

Skin Therapy Letter
|May 23, 2024
PubMed

Intravenous immune globulin (IVIG) is a manufactured blood product commonly used to treat immunodeficiency syndromes, inflammatory disorders, and autoimmune diseases of the skin. The use of IVIG in dermatology has evolved and expanded over time, serving as a useful therapeutic intervention for several inflammatory skin disorders. In addition to demonstrating efficacy in treating several cutaneous pathologies, IVIG also mitigates the need for steroids or other immunosuppressant medications in many dermatologic diseases. This review highlights the evidence for IVIG use across several dermatologic conditions, emphasizing the dosing regimens and safety considerations.

Keywords:
IVIGStevens-Johnson syndromeautoimmune diseasesbullous dermatosesdermatomyositisimmunomodulationintravenous immunoglobulin

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