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Association between life's essential 8 and overactive bladder
Guoliang Feng1, Shaoqun Huang2, Weimin Zhao3
1Department of Oncology, Nanchang Third Hospital, Nanchang, Jiangxi, China.
Scientific Reports
|May 23, 2024
Summary
Improving cardiovascular health (CVH) through Life's Essential 8 (LE8) metrics is linked to lower overactive bladder (OAB) risk. Higher LE8 scores significantly reduce OAB prevalence, highlighting the importance of cardiovascular wellness.
Area of Science:
- Cardiology
- Urology
- Public Health
Background:
- Overactive bladder (OAB) and cardiovascular health (CVH) connections are under-researched.
- Cardiovascular health is crucial for overall well-being, yet its link to OAB requires further investigation.
Purpose of the Study:
- To investigate the association between cardiovascular health, measured by Life's Essential 8 (LE8) scores, and the prevalence of overactive bladder (OAB) in American adults.
- To analyze how different components of cardiovascular health (behaviors and factors) relate to OAB risk.
Main Methods:
- Utilized data from 70,190 participants in the National Health and Nutrition Examination Survey (2005-2018).
- Employed multivariable logistic regression and restricted cubic splines to assess the relationship between LE8 scores and OAB.
- Conducted subgroup analyses to explore interactions, such as with smoking status.
Main Results:
- A significant negative correlation was found between higher LE8 scores and OAB prevalence.
- A 10-point increase in LE8 score was associated with a 17% decrease in the odds of OAB.
- Individuals with higher LE8 scores had a 46% lower probability of experiencing OAB compared to those with lower scores.
Conclusions:
- Optimizing cardiovascular health, as indicated by LE8 scores, is associated with a reduced likelihood of developing overactive bladder.
- Both overall cardiovascular health and its individual components (behaviors and factors) play a role in OAB risk.
- Smoking status significantly interacts with cardiovascular health in relation to OAB prevalence, underscoring the importance of smoking cessation.
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