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Pediatric catastrophic antiphospholipid syndrome with extensive skin involvement
Swetalina Pradhan1, Asmita Sinha2, Gaurav Dash1
1Department of Dermatology, All India Institute of Medical Sciences, Patna, India.
Abstract:
Antiphospholipid syndrome (APS) is a state of hypercoagulability due to persistent antiphospholipid antibodies (aPLs) in the blood. Catastrophic APS (CAPS) is a severe form with higher morbidity and mortality in which there occurs widespread thrombosis in multiple organs and hence warrants early diagnosis and aggressive management. We report a case of pediatric CAPS with extensive cutaneous involvement precipitated by infection successfully treated with the combination of high dose systemic corticosteroids, antibiotics, long-term anticoagulation, and wound care.
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