Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Biopharmaceutics and Pharmacokinetics: Overview01:28

Biopharmaceutics and Pharmacokinetics: Overview

2.0K
Understanding drugs, drug products, and their performance in pharmaceutical science is pivotal. Drugs, whether simple molecules or complex compounds, are designed to interact with the body's biological systems to diagnose, treat, or prevent diseases. Drug products include various delivery systems such as tablets, capsules, injections, and inhalers. The performance of these drug products is gauged by their ability to deliver the active ingredient to the desired site of action at the...
2.0K
Factors Affecting Drug Response: Overview01:21

Factors Affecting Drug Response: Overview

2.0K
When it comes to infants and young children, they are typically administered smaller doses of medication in comparison to adults. This is primarily because their organ functions still need to fully develop, meaning their bodies are not as efficient at metabolizing or eliminating drugs. Additionally, their blood-brain barrier is more permeable than in adults. As a result, high concentrations of drugs can easily penetrate the central nervous system (CNS), potentially leading to neurological...
2.0K
Drug Dosage Regimen: Overview01:15

Drug Dosage Regimen: Overview

3.5K
A drug dosage regimen describes the specific instructions and schedule for administering a drug to a patient. It considers factors such as drug dosage, frequency, route of administration, and duration of treatment. Designing an appropriate dosage regimen for a patient aims to achieve a target drug concentration at the site of action.
Typically, the starting dose and dosing interval are guided by the manufacturer's recommendations based on clinical trials conducted during and after drug...
3.5K
Pharmacokinetics: Overview01:10

Pharmacokinetics: Overview

6.3K
Pharmacokinetics is a scientific discipline that focuses on the journey of a drug within the body, encompassing four key stages: absorption, distribution, metabolism, and elimination. The first stage, absorption, involves the drug's transfer into the bloodstream. Several factors dictate the extent and speed of this process. For example, the liver often metabolizes oral drugs before they reach systemic circulation, leading to only partial absorption. In contrast, intravenous (IV)...
6.3K
Bioequivalence: Overview01:16

Bioequivalence: Overview

1.0K
Pharmaceutical equivalents, by definition, are drug products with the same active ingredient in the same quantities, encapsulated in identical dosage forms, and intended for the same administration routes. These pharmaceutical equivalents are deemed bioequivalent if the bioavailability of the active entity in the drug preparations is similar. Moreover, pharmaceutical equivalents demonstrating bioequivalence are also regarded as therapeutically equivalent. This means that when used as directed,...
1.0K
Analysis of Population Pharmacokinetic Data01:12

Analysis of Population Pharmacokinetic Data

252
Analysis of population pharmacokinetic data involves studying the behavior of drugs within diverse populations to understand their pharmacokinetic parameters. Traditional pharmacokinetic methods typically involve collecting samples from a few individuals and estimating these parameters. While these methods are commonly used, they have limitations in capturing the variability in drug response among individuals or heterogeneous populations. Population pharmacokinetics is employed to address these...
252

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Aspirin Withdrawal in Patients With Coronary Artery Disease.

Journal of the American College of Cardiology·2026
Same author

Hydrocodone vs Oxycodone and Postoperative Pain and Opioid Use in Joint Arthroplasty.

JAMA network open·2026
Same author

Predicting in vitro fertilization success: establishing human chorionic gonadotropin cutoffs after frozen embryo transfers for untested and preimplantation genetic tested embryos.

Journal of assisted reproduction and genetics·2026
Same author

Machine Learning With Genetic and Clinical Data to Predict Ischemic Outcomes After PCI.

Clinical and translational science·2026
Same author

Integrating genomic medicine into primary care: a precision health model from Riyadh, Saudi Arabia.

Family medicine and community health·2026
Same author

Prevalence of CYP2C19 polymorphisms in medically and surgically managed patients with GERD.

Surgery·2026

Related Experiment Video

Updated: Jun 25, 2025

Targeted Next-generation Sequencing and Bioinformatics Pipeline to Evaluate Genetic Determinants of Constitutional Disease
09:34

Targeted Next-generation Sequencing and Bioinformatics Pipeline to Evaluate Genetic Determinants of Constitutional Disease

Published on: April 4, 2018

33.7K

Assessing user perspectives on clinical pharmacogenomics consultation documentation: a user-centered evaluation.

Nina Desai1, Namratha Ravindra1, Bradley Hall1

  • 1Department of Pharmacotherapy of Translational Research and Center for Pharmacogenomics and Precision Medicine, College of Pharmacy, University of Florida, Gainesville, FL, United States.

Frontiers in Pharmacology
|May 24, 2024
PubMed
Summary

This study improved pharmacogenomics (PGx) result notes for healthcare providers by incorporating their feedback. Revisions focused on clarity in sections like phenoconversion and medication lists for better clinical integration.

Keywords:
SOAP noteconsultationpharmacogenomicsphenoconversionuser-centered evaluation

More Related Videos

Candidate Gene Testing in Clinical Cohort Studies with Multiplexed Genotyping and Mass Spectrometry
05:53

Candidate Gene Testing in Clinical Cohort Studies with Multiplexed Genotyping and Mass Spectrometry

Published on: June 21, 2018

10.1K
Integration of Wet and Dry Bench Processes Optimizes Targeted Next-generation Sequencing of Low-quality and Low-quantity Tumor Biopsies
13:24

Integration of Wet and Dry Bench Processes Optimizes Targeted Next-generation Sequencing of Low-quality and Low-quantity Tumor Biopsies

Published on: April 11, 2016

11.8K

Related Experiment Videos

Last Updated: Jun 25, 2025

Targeted Next-generation Sequencing and Bioinformatics Pipeline to Evaluate Genetic Determinants of Constitutional Disease
09:34

Targeted Next-generation Sequencing and Bioinformatics Pipeline to Evaluate Genetic Determinants of Constitutional Disease

Published on: April 4, 2018

33.7K
Candidate Gene Testing in Clinical Cohort Studies with Multiplexed Genotyping and Mass Spectrometry
05:53

Candidate Gene Testing in Clinical Cohort Studies with Multiplexed Genotyping and Mass Spectrometry

Published on: June 21, 2018

10.1K
Integration of Wet and Dry Bench Processes Optimizes Targeted Next-generation Sequencing of Low-quality and Low-quantity Tumor Biopsies
13:24

Integration of Wet and Dry Bench Processes Optimizes Targeted Next-generation Sequencing of Low-quality and Low-quantity Tumor Biopsies

Published on: April 11, 2016

11.8K

Area of Science:

  • Precision Medicine
  • Genomic Medicine
  • Clinical Informatics

Background:

  • The University of Florida Health Precision Medicine Program delivers pharmacogenomics (PGx) results to requesting providers.
  • A lack of formal needs assessment and best practice guidelines hinders optimal PGx note development.
  • Effective communication of PGx results is essential for clinical decision-making.

Purpose of the Study:

  • To enhance the content and format of PGx consult notes at UF Health.
  • To incorporate healthcare provider feedback into the design of PGx result notes.
  • To improve the usability and clarity of PGx information for clinical application.

Main Methods:

  • Conducted in-depth user sessions with 11 healthcare providers.
  • Evaluated the usability of the existing PGx consult note template.
  • Gathered qualitative feedback on specific sections of the PGx note.

Main Results:

  • Overall satisfaction with the current PGx note content was reported.
  • Specific sections, including phenoconversion and the medication list, were identified for improvement.
  • Provider feedback highlighted areas needing enhanced clarity and usability.

Conclusions:

  • Provider feedback is crucial for optimizing PGx consult note design.
  • Revisions to specific sections can improve the clarity and utility of PGx notes.
  • This user-centered approach supports the effective integration of pharmacogenomics into clinical practice.