Graphene as a promising material in orthodontics: A review

Graphene is an extraordinary material with unique mechanical, chemical, and thermal properties. Additionally, it boasts high surface area and antimicrobial properties, making it an attractive option for researchers exploring innovative materials for biomedical applications. Although there have been various studies on graphene applications in different biomedical fields, limited reviews have been conducted on its use in dentistry, and no reviews have focused on its application in the orthodontic field. This review aims to present a comprehensive overview of graphene-based materials, with an emphasis on their antibacterial mechanisms and the factors that influence these properties. Additionally, the review summarizes the dental applications of graphene, spotlighting the studies of its orthodontic application as they can be used to enhance the antibacterial and mechanical properties of orthodontic materials such as adhesives, archwires, and splints. Also, they can be utilized to enhance bone remodeling during orthodontic tooth movement. An electronic search was carried out in Scopus, PubMed, Science Direct, and Wiley Online Library digital database platforms using graphene and orthodontics as keywords. The search was restricted to English language publications without a time limit. This review highlights the need for further laboratory and clinical research using graphene-based materials to improve the properties of orthodontic materials to make them available for clinical use.