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Updated: Jun 25, 2025

Author Spotlight: Alleviating Nausea and Vomiting in Pregnancy with Safe and Effective Auricular Acupuncture
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Akathisia and oculogyric crisis in hyperemesis gravidarum

Adam Morton1, Conor Mackle2, Julian Pavey3

  • 1Obstetric Medicine, Mater Health, Raymond Terrace, South Brisbane, Herston, Queensland, Australia.

Obstetric Medicine
|May 24, 2024
PubMed

Hyperemesis gravidarum complicates 0.5-2% of pregnancies. HG is associated with insomnia, significantly increased risks of anxiety and depression, and may be associated with feelings of guilt, social isolation and thoughts of suicidal ideation or termination of pregnancy. Anti-emetic therapy may be complicated by akathisia and dystonic reactions, which may affect the ongoing management of nausea and vomiting. A case of akathisia and oculogyric crisis following the addition of parenteral prochlorperazine to ondansetron and metoclopramide is presented. The treatment options for extrapyramidal side effects with anti-emetics in pregnancy and for ongoing treatment of nausea and vomiting are discussed.

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