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Related Experiment Video

Updated: Jun 25, 2025

Endoscopic Endonasal Trans-sphenoidal Approach: Minimally Invasive Surgery for Pituitary Adenomas
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Optimizing Surgical Management of Acute Invasive Fungal Sinusitis.

Lalee Varghese1, Regi Kurien1, Lisa Mary Cherian1

  • 1Department of Otorhinolaryngology, Christian Medical College, Vellore, India.

Turkish Archives of Otorhinolaryngology
|May 24, 2024
PubMed
Summary

Tailored surgical guidelines for acute invasive fungal sinusitis (AIFS) ensure effective debridement and optimal function. These conservative approaches minimize the need for repeat surgeries, leading to favorable patient outcomes.

Keywords:
Fungal sinusitisdebridementendoscopyguidelinemucormycosisrevision surgerysurgery

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Area of Science:

  • Otolaryngology
  • Surgical Oncology
  • Infectious Diseases

Background:

  • Acute invasive fungal sinusitis (AIFS) requires prompt surgical intervention for optimal outcomes.
  • Developing standardized, conservative surgical guidelines is crucial for managing AIFS effectively and avoiding repeat debridement.

Purpose of the Study:

  • To propose tailored, conservative surgical guidelines for AIFS based on anatomical involvement.
  • To evaluate the efficacy of these guidelines in preventing revision surgeries and ensuring favorable patient outcomes.

Main Methods:

  • A retrospective observational study involving 150 AIFS patients who underwent surgery guided by the proposed protocol.
  • Data collection included patient demographics, comorbidities, surgical procedures, need for revision surgery, and overall outcomes.
  • Analysis focused on the correlation between disease extent, comorbidities, COVID-19 status, and the requirement for revision debridement.

Main Results:

  • 150 patients underwent endoscopic sinonasal debridement; 72% had recent COVID-19 infection.
  • 61.3% required additional procedures, and 15.4% needed revision surgery.
  • Patients recovered from COVID-19 or with no comorbidities had no revision surgeries; age, gender, and comorbidities were not significant predictors for revision.

Conclusions:

  • The proposed surgical guidelines for AIFS facilitate adequate debridement while preserving function.
  • Low revision surgery rates and excellent outcomes with minimal morbidity validate the usefulness of these tailored surgical approaches.