The effects of psychological interventions on suicide for cancer patients: a systematic review and network

Xinyue Zhang1, Dan Zhang2, Yuqi Liu1

  • 1School of Nursing & Rehabilitation, Shandong University, Jinan, Shandong, China.

PubMed

Insights

Empathy therapy is the most effective psychological intervention for reducing suicidal and death ideation (SDI) and suicidal behavior in cancer patients, according to a network meta-analysis. Comprehensive psychological intervention also showed significant benefits.

Area of Science:

  • Oncology
  • Psychology
  • Evidence-Based Medicine

Background:

  • Cancer patients frequently experience suicidal and death ideation (SDI) and suicidal behavior.
  • A variety of psychological interventions exist, but their comparative effectiveness for this population is not well-established.

Purpose of the Study:

  • To identify the optimal psychological interventions for reducing SDI and suicidal behavior in cancer patients.
  • To compare the efficacy of different psychological interventions through a network meta-analysis.

Main Methods:

  • A systematic search of seven databases was conducted until April 8, 2022.
  • A pairwise and network meta-analysis was performed on 8 studies involving 1,350 cancer patients.
  • Efficacy was determined using standardized mean differences (SMDs) and 95% confidence intervals (CIs), with Surface Under the Cumulative Rankings Curve (SUCRA) used for ranking.

Main Results:

  • Empathy therapy demonstrated the highest efficacy (SUCRA = 95.3%) among the six interventions evaluated.
  • Comprehensive psychological intervention (SUCRA = 77.6%) and meaning-centered therapy (SUCRA = 40.7%) were also ranked.
  • No significant publication bias was detected through comparison-adjusted funnel plots, and sensitivity analyses confirmed the robustness of the findings.

Conclusions:

  • Empathy therapy is identified as the optimal psychological intervention for reducing suicidal and death ideation and suicidal behaviors in cancer patients.
  • Further high-quality, multi-center randomized controlled trials are recommended to strengthen these conclusions.

Related Concept Videos

Cancer Survival Analysis01:21

Cancer Survival Analysis

Cancer survival analysis focuses on quantifying and interpreting the time from a key starting point, such as diagnosis or the initiation of treatment, to a specific endpoint, such as remission or death. This analysis provides critical insights into treatment effectiveness and factors that influence patient outcomes, helping to shape clinical decisions and guide prognostic evaluations. A cornerstone of oncology research, survival analysis tackles the challenges of skewed, non-normally...
343
Psychosurgery01:30

Psychosurgery

Psychosurgery, the surgical alteration or permanent removal of brain tissue to alleviate severe psychological conditions, stands as one of the most radical and controversial treatments in the history of mental health care. Its development and application have evolved significantly, marked by dramatic shifts in scientific understanding and ethical perspectives.
Historical Development of Psychosurgery
In the 1930s, Portuguese neurologist Antonio Egas Moniz introduced a surgical procedure designed...
53
Cancer Therapies02:49

Cancer Therapies

Cancer therapies are various modes of treatment, such as surgery, radiation therapy, and chemotherapy that are administered to cancer patients.
However, cancer treatments can pose several challenges, as therapies used to kill cancer cells are generally also toxic to normal cells. Moreover, cancer cells mutate rapidly and can develop resistance to chemical agents or radiation therapy. Besides, all types of cancer cells may not respond to the same therapy. Some cancer cells respond to one...
7.6K
Psychoneuroimmunology: Diabetes and Cancer01:19

Psychoneuroimmunology: Diabetes and Cancer

Chronic stress has been linked to both the onset and progression of serious health conditions, including Type 2 diabetes and cancer. Type 2 diabetes, a widespread chronic illness, is closely associated with obesity and insulin resistance, both of which often worsen under stress. Studies indicate that men experiencing high levels of chronic stress face a 45% higher risk of developing diabetes compared to those with minimal stress. Stress triggers physiological responses that elevate blood...
28
Psychological and Sociocultural Causes of Schizophrenia01:29

Psychological and Sociocultural Causes of Schizophrenia

Schizophrenia, a complex psychiatric disorder, has been historically misunderstood. Early psychological theories attributed its origins to childhood trauma and unresponsive parenting. However, contemporary research largely rejects these notions, favoring the vulnerability-stress hypothesis. This model proposes that individuals with a genetic predisposition to schizophrenia may develop the disorder following exposure to significant environmental stressors. Notably, studies on high-risk...
83
Elements Crucial for Effective Psychotherapy01:25

Elements Crucial for Effective Psychotherapy

Research has highlighted several critical factors that influence the effectiveness of psychotherapy, such as the therapeutic alliance, the therapist, and the client.
The Therapeutic Alliance
The therapeutic alliance refers to the relationship between the therapist and the client. The alliance strengthens when the therapist and the client engage in a nurturing, supportive, trusting, empathetic, and respectful relationship, improving therapeutic outcomes. Therapists must monitor this relationship...
41