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Updated: Jun 20, 2026

Isolation, Characterization, and Therapeutic Application of Extracellular Vesicles from Cultured Human Mesenchymal Stem Cells
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Isolation, Characterization, and Therapeutic Application of Extracellular Vesicles from Cultured Human Mesenchymal Stem Cells

Published on: September 23, 2022

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hTERT-Immortalized Mesenchymal Stem Cell-Derived Extracellular Vesicles: Large-Scale Manufacturing, Cargo Profiling,

Jessica Hindle1, Anastasia Williams2, Yuriy Kim2

  • 1ATCC, Manassas, VA 20110, USA.

Cells
|May 24, 2024
PubMed
Summary

Human telomerase reverse transcriptase (hTERT)-immortalized mesenchymal stem cell extracellular vesicles (EVs) show reparative effects on damaged retinal cells. This study establishes a reproducible manufacturing platform for these therapeutic EVs.

Keywords:
extracellular vesicles (EVs)hTERT-immortalized mesenchymal stem cellsionizing radiation (IR)retinal pigment epithelium (RPE) cells

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