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Updated: Jun 25, 2025

Regulatory T cells: Therapeutic Potential for Treating Transplant Rejection and Type I Diabetes
Published on: August 20, 2007
Rephrasing the 'David-Goliath' story in the field of diabetes
1Amity Institute of Biotechnology, Amity University, Room No. 504, Academic Building Plot No: 36, 37 & 38, Major Arterial Road, Action Area II Kadampukur Village, Rajarhat, Newtown Kolkata, West Bengal, 700135, India. ndey@kol.amity.edu.
Abstract:
Diabetes Mellitus has become a serious threat to public health. This non-communicable disease is spreading like wildfire to shape in the form of a global pandemic. It affects several organs during silent progression in the human body. The pathophysiological fallouts associate dysregulation of numerous cellular pathways. MicroRNAs have emerged as potent gene expression regulators by post-transcriptional mechanisms in the last two decades or so. Many microRNAs display differential expression patterns under hyperglycemia affecting coupled cellular signaling cascades. The present article attempts to unfold the involvement of microRNAs as biomarkers in diabetic conditions in current scenarios identifying their therapeutic significance.
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