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Updated: Jul 7, 2026

Implantation of the Syncardia Total Artificial Heart
Published on: July 18, 2014
Severe functional mitral regurgitation and cardiogenic shock after transcatheter aortic valve replacement
Oludamilola Akinmolayemi1, Charlotte McCreery2, Francesca Romana Prandi1
1Mount Sinai Fuster Heart Hospital, Icahn School of Medicine at Mount Sinai, New York, New York, USA.
An elderly woman with severe aortic stenosis requiring valve replacement also had significant coronary artery disease. This finding highlights the complexity of managing multiple cardiovascular conditions in older patients.
Area of Science:
- Cardiology
- Interventional Cardiology
- Geriatric Medicine
Background:
- Severe aortic stenosis is a critical valvular heart disease often requiring intervention.
- Transcatheter aortic valve replacement (TAVR) is a standard treatment for symptomatic severe aortic stenosis.
- Older adults frequently present with multiple comorbidities, complicating treatment decisions.
Observation:
- An 83-year-old female patient presented with symptomatic severe aortic stenosis.
- The patient was referred for transcatheter aortic valve replacement (TAVR).
- Diagnostic left heart catheterization was performed.
Findings:
- Left heart catheterization revealed diffuse 3-vessel coronary artery disease.
- The patient's condition indicates complex cardiovascular disease requiring comprehensive management.
Implications:
- Coexistence of severe aortic stenosis and multi-vessel coronary artery disease necessitates careful pre-procedural planning.
- Treatment strategies must balance the risks and benefits of addressing both valvular and coronary pathologies.
- Multidisciplinary heart team approach is crucial for optimizing outcomes in patients with complex cardiac conditions.
Related Concept Videos
Mitral Regurgitation I: Introduction
Mitral Regurgitation II: Clinical Features and Diagnostic Tests
Mitral Regurgitation III: Medical Management
Aortic Regurgitation I: Introduction
Aortic Regurgitation II: Clinical Features and Diagnostic Tests
Aortic Regurgitation III: Medical Management

