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Updated: Jun 25, 2025

In Vivo Immunogenicity Screening of Tumor-Derived Extracellular Vesicles by Flow Cytometry of Splenic T Cells
Published on: September 23, 2021
Exosomes/Extracellular Vesicles and Targeted Tumor Immunotherapy
Chiara Corrado1, Simona Fontana1
1Department of Biomedicine, Neurosciences and Advanced Diagnostics, University of Palermo, 90133 Palermo, Italy.
Abstract:
This Special Issue intends to underscore several topics related to cellular signaling transduction, considering the consensus that nowadays, the best scientific approach for the prevention, diagnosis, and treatment of several diseases is the study of the regulatory networks that determine the response to therapy and the maintenance of homeostasis or its dysregulation [...].
Insights
This Special Issue explores cellular signaling transduction, emphasizing its role in disease prevention, diagnosis, and treatment. Understanding regulatory networks is key to maintaining homeostasis and improving therapeutic responses.
Area of Science:
- Cellular and Molecular Biology
- Biochemistry
- Physiology
Background:
- Cellular signaling transduction pathways are fundamental to biological processes.
- Dysregulation of these pathways is implicated in various diseases.
- Understanding regulatory networks is crucial for modern medicine.
Discussion:
- This Special Issue focuses on the critical role of cellular signaling in health and disease.
- It highlights the importance of studying regulatory networks for therapeutic advancements.
- The consensus supports a systems biology approach for disease management.
Key Insights:
- Cellular signaling transduction is central to homeostasis and disease pathogenesis.
- Investigating regulatory networks informs prevention, diagnosis, and treatment strategies.
- Therapeutic response and disease outcomes are linked to signaling pathway modulation.
Outlook:
- Future research will further elucidate complex signaling networks.
- This understanding will drive the development of targeted therapies.
- Advances in cellular signaling will revolutionize personalized medicine.
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