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Updated: Jun 25, 2025

Facile Preparation of 4-Substituted Quinazoline Derivatives
Published on: February 15, 2016
Recent Advances in Metal-Catalyzed Approaches for the Synthesis of Quinazoline Derivatives
Nitesh K Nandwana1, Om P S Patel2, Manish K Mehra1
1Medicinal Chemistry and Molecular and Cellular Oncogenesis (MCO) Program, The Wistar Institute, Philadelphia, PA 19104, USA.
Abstract:
Quinazolines are an important class of heterocyclic compounds that have proven their significance, especially in the field of organic synthesis and medicinal chemistry because of their wide range of biological and pharmacological properties. Thus, numerous synthetic methods have been developed for the synthesis of quinazolines and their derivatives. This review article briefly outlines the new synthetic methods for compounds containing the quinazoline scaffold employing transition metal-catalyzed reactions.
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